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What is the impact of systematically missing exposure data on air pollution health effect estimates?

机译:系统地丢失暴露数据对空气污染健康影响估算有什么影响?

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摘要

Time-series studies reporting associations between daily air pollution and health use pollution data from monitoring stations that vary in the frequency of recording. Within the Air Pollution and Health: A European and North American Approach (APHENA) project, we evaluated the impact of systematically missing daily measurements on the estimated effects of PM10 and ozone on daily mortality. For four cities with complete time-series data, we created patterns of systematically missing exposure measurements by deleting observations. Poisson regression-derived city-specific estimates were combined to produce overall effect estimates. Analyses based on incomplete time series gave considerably lower pooled PM10 and ozone health effects compared to those from complete data. City-specific estimates were generally lower although more variable. Systematically missing exposure data for air pollutants appears to lead to underestimation of associated health effects. Our findings indicate that the use of evidence from studies with incomplete exposure data may underestimate the impact of air pollution and highlight the advantage of having complete daily data in time-series studies.
机译:时间序列研究报告了每日空气污染与来自监测站的卫生使用污染数据之间的关联,这些数据的记录频率有所不同。在“空气污染与健康:欧洲和北美方法”(APHENA)项目中,我们评估了系统地缺少每日测量值对PM10和臭氧对每日死亡率的估计影响的影响。对于四个具有完整时间序列数据的城市,我们通过删除观测值来创建系统地缺少暴露量测量值的模式。结合Poisson回归得出的特定于城市的估算值,可以得出总体效果估算值。与完整数据相比,基于不完整时间序列的分析得出的PM10和臭氧对健康的综合影响要低得多。尽管变化较大,但特定于城市的估计值通常较低。系统地缺少空气污染物的暴露数据似乎导致对相关健康影响的低估。我们的发现表明,使用来自暴露数据不完整的研究的证据可能会低估空气污染的影响,并突出显示在时序研究中拥有完整的每日数据的优势。

著录项

  • 来源
    《Air quality, atmosphere & health》 |2014年第4期|415-420|共6页
  • 作者单位

    1.Department of Hygiene Epidemiology and Medical Statistics Medical School University of Athens 75 Mikras Asias Str 115 27 Athens Greece;

    2.Department of Biostatistics John Hopkins Bloomberg School of Public Health 615 North Wolfe Street Baltimore MD 21205-2179 USA;

    3.Department of Epidemiology and Community Medicine University of Ottawa 1 Stewart Street Ottawa ON K1N 6N5 Canada;

    1.Department of Hygiene Epidemiology and Medical Statistics Medical School University of Athens 75 Mikras Asias Str 115 27 Athens Greece;

    4.Department of Biostatistics Harvard School of Public Health 655 Huntington Avenue Boston MA 02115 USA;

    5.MRC-PHE Centre for Environment and Health St George’s University of London Cranmer Terrace London SW17 0RE UK;

    6.Department of Environmental Health Harvard School of Public Health 655 Huntington Avenue Boston MA 02115 USA;

    7.Environmental Health Department French Institute for Public Health Surveillance (InVS) 12 du Val d’Osne Str 94415 Saint-Maurice France;

    5.MRC-PHE Centre for Environment and Health St George’s University of London Cranmer Terrace London SW17 0RE UK;

    6.Department of Environmental Health Harvard School of Public Health 655 Huntington Avenue Boston MA 02115 USA;

    8.Health Effects Institute 101 Federal Street Boston MA 02110-1817 USA;

    3.Department of Epidemiology and Community Medicine University of Ottawa 1 Stewart Street Ottawa ON K1N 6N5 Canada;

    9.Department of Preventive Medicine Keck School of Medicine University of Southern California 1975 Zonal Avenue Los Angeles CA 90089-9034 USA;

    1.Department of Hygiene Epidemiology and Medical Statistics Medical School University of Athens 75 Mikras Asias Str 115 27 Athens Greece;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Air pollution; Monitoring; Short-term effects; Systematically missing; Time-series analysis;

    机译:空气污染;监测;短期影响;系统缺失;时间序列分析;

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