首页> 外文期刊>Air quality, atmosphere & health >Associations between source-indicative pollution metrics and increases in pulmonary inflammation and reduced lung function in a panel of asthmatic children
【24h】

Associations between source-indicative pollution metrics and increases in pulmonary inflammation and reduced lung function in a panel of asthmatic children

机译:指示性污染指标与一组哮喘儿童的肺部炎症增加和肺功能下降之间的关联

获取原文
获取原文并翻译 | 示例
       

摘要

Exposure to traffic-related air pollution may pose an elevated risk of respiratory harm to asthmatic children. The goal of this study was to investigate the association between exposure to specific classes of air pollutants and respiratory response in a panel of asthmatic children in El Paso, Texas. Air pollution and health response was measured at two elementary schools in El Paso with different levels of air pollution exposure. A high-exposure school was adjacent to the U.S.–Mexico border in close proximity to a major border crossing for diesel truck traffic, while the low-exposure school was in a suburban area distant from major roadways. The indoor and outdoor concentration of particle- and gas-phase pollutants was measured at each school for 13 weeks. Speciation of pollutants was performed to help identify sources. Each week, a panel of 38 asthmatic students performed pulmonary function and exhaled nitric oxide tests and completed asthma symptom questionnaires. Changes in both lung function and airway inflammation were significantly associated with pollutants with known traffic-related sources. FEV1 declined by up to 5 % in association with an interquartile range increase in the concentration of volatile organic compounds with traffic sources. Exhaled nitric oxide increased 1–5 % in association with these same compounds as well as with particulate black carbon (which also has a traffic-related source). No associations were observed between health response and pollutants with non-roadway sources. Exposure to traffic-related air pollution may lead to increased airway inflammation and decreased lung function in asthmatic children.
机译:暴露于与交通有关的空气污染中可能会对哮喘儿童产生呼吸道伤害的高风险。这项研究的目的是调查得克萨斯州埃尔帕索的一组哮喘儿童中暴露于特定类别的空气污染物与呼吸系统反应之间的关系。在埃尔帕索的两所小学,测量了不同的空气污染暴露水平,得出空气污染和健康反应。一所高暴露学校靠近美墨边境,靠近一个主要的柴油卡车交通过境点,而低暴露学校则位于远离主要道路的郊区。在每所学校进行了13周的室内和室外颗粒和气相污染物浓度测量。进行了污染物的形态分析以帮助识别来源。每周,由38名哮喘学生组成的小组进行肺功能和呼出气一氧化氮测试,并完成哮喘症状问卷调查。肺功能和气道炎症的变化与已知交通相关来源的污染物显着相关。 FEV1下降高达5%,这与交通源中挥发性有机化合物的浓度在四分位数范围内增加有关。呼出的一氧化氮与这些相同的化合物以及与微粒黑炭(也有与交通有关的来源)有关,增加了1-5%。在健康反应与非道路来源污染物之间未发现关联。接触交通相关的空气污染可能导致哮喘儿童的呼吸道炎症增加和肺功能下降。

著录项

  • 来源
    《Air quality, atmosphere & health》 |2013年第2期|487-499|共13页
  • 作者单位

    1.Department of Environmental Health Rollins School of Public Health Emory University 1518 Clifton Road Atlanta GA 30322 USA;

    1.Department of Environmental Health Rollins School of Public Health Emory University 1518 Clifton Road Atlanta GA 30322 USA;

    2.Department of Civil Engineering University of Texas at El Paso El Paso TX USA;

    2.Department of Civil Engineering University of Texas at El Paso El Paso TX USA;

    3.Department of Biostatistics and Bioinformatics Rollins School of Public Health Emory University Atlanta GA USA;

    4.Division of Epidemiology School of Public Health University of Texas Health Science Center at Houston Houston TX USA;

    5.Division of Pulmonary Allergy and CCM University of Pittsburgh Medical Center Pittsburgh PA USA;

    2.Department of Civil Engineering University of Texas at El Paso El Paso TX USA;

    1.Department of Environmental Health Rollins School of Public Health Emory University 1518 Clifton Road Atlanta GA 30322 USA;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Traffic pollution; BTEX; Exhaled nitric oxide; Lung function; Asthma control;

    机译:交通污染BTEX呼出气一氧化氮肺功能哮喘控制;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号