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首页> 外文期刊>American Journal of Neuroradiology >Restored Activation of Primary Motor Area from Motor Reorganization and Improved Motor Function after Brain Tumor Resection
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Restored Activation of Primary Motor Area from Motor Reorganization and Improved Motor Function after Brain Tumor Resection

机译：肿瘤切除后通过运动重组恢复了主要运动区的激活并改善了运动功能

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摘要

BACKGROUND AND PURPOSE: Reorganization of brain function may result in preservation of motor function in patients with brain tumors. The goal of the present study was to investigate whether function of the primary motor area (M1) was restored and whether motor function improved after brain tumor resection. METHODS: Five patients with metastatic brain tumors located within or near M1 underwent awake surgery with intraoperative cortical mapping and continuous task monitoring. Preoperative and postoperative functional MR imaging (fMRI) was performed during hand clenching, and diffusion tensor imaging (DTI) was performed in 1 case to further characterize the area activated in fMRI. RESULTS: Preoperative fMRI performed during hand clenching demonstrated reorganization of motor function. In patients with severe paresis (cases 3, 4, and 5), clenching of the affected hand induced a large blood oxygen level–dependent response in the right hemisphere, mainly in the anterior temporal lobe, despite the location site of the tumor. Postoperative fMRI during hand clenching demonstrated activation of the contralateral M1. Furthermore, in case 5, DTI detected tracts, possibly the inferior longitudinal fasciculus, arising from anterior temporal activated area as well as tracts connecting the premotor and M1 activated area. This patient demonstrated mirror movement of the hand during the course of motor function recovery. CONCLUSIONS: Tumor resection resulted in restoration of M1 function and improved motor function in patients with preoperative reorganization of M1 function. Furthermore, the preoperative reorganization of motor function in cases with severe paresis may be related to changes in the right hemisphere, including the temporal lobe.
机译：背景与目的：脑功能的重组可能会导致患有脑肿瘤的患者运动功能的保持。本研究的目的是研究脑肿瘤切除后是否恢复了原发性运动区域（M1）的 功能，以及是否改善了 运动功能。 和术后功能性MR成像（fMRI），并进一步进行了扩散张量成像（DTI）1例。结果表明：在手握紧过程中进行的术前功能磁共振成像证实了运动功能的重新组织。 在严重轻瘫 （3、4和5例）的患者中，患病的手紧握会导致 在右侧 < / sup>半球，主要位于颞叶前部，尽管肿瘤位于 位置。双手紧握期间的术后fMRI 证明了对侧M1的激活。此外， 在情况5中，DTI检测到了由前颞部激活区域as 以及连接前运动的区域所引起的束，可能是纵向纵束 该患者表现出在运动功能恢复过程中手的镜面运动。 结论：肿瘤切除术使手法恢复。 M1功能的术前重组 患者的M1功能 和运动功能改善。此外，严重轻瘫患者的运动功能的术前重组 可能与 与右半球的变化有关，包括颞叶。

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  • 来源
    《American Journal of Neuroradiology》 |2006年第6期|00001275-00001282|共8页
  • 作者

    N. Shinoura; Y. Suzuki; R. Yamada; T. Kodama; M. Takahashi; K. Yagi;

  • 作者单位

    Department of Neurosurgery, Komagome Metropolitan Hospital, Tokyo, Japan;

    Department of Radiologic Technology, Tokyo Metropolitan University of Health Sciences, Tokyo, Japan;

    Department of Neurosurgery, Komagome Metropolitan Hospital, Tokyo, Japan;

    Department of Radiologic Technology, Tokyo Metropolitan University of Health Sciences, Tokyo, Japan;

    Department of Neurosurgery, Komagome Metropolitan Hospital, Tokyo, Japan;

    Department of Radiologic Technology, Tokyo Metropolitan University of Health Sciences, Tokyo, Japan;

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