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首页> 外文期刊>American Journal of Neuroradiology >Cerebellar Cortical Dysplasia: MR Findings in a Complex Entity
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Cerebellar Cortical Dysplasia: MR Findings in a Complex Entity

机译：小脑皮质发育不良：复杂实体中的MR发现。

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BACKGROUND AND PURPOSE: MR imaging findings of cerebellar cortical dysplasia have been described as a new cerebellar malformation. The purpose of this study was to assess the association of cerebellar cortical dysplasia with other cerebral malformations. METHODS: We retrospectively reviewed 46 MR examinations of patients presenting with developmental delay, hypotonia, and facial deformities to identify abnormal folia or fissures or both within cerebellar hemispheres or vermis suggesting cortical dysplasia. RESULTS: Cerebellar cortical dysplasia was diagnosed in 17 patients. In two patients, it was isolated. In the remaining 15 patients, the malformation was associated with vermian malformation (n=11), cerebral cortical dysplasias (n=8), dysplasia of corpus callosum (n=6), and heterotopia (n=5). A widespread malformation of the posterior fossa was observed in eight patients (Dandy-Walker, Chiari II and III, and hypoplasia of brain stem). One patient with hypertrophied cerebellar hemisphere had minor enlargement of the right cerebral hemisphere and lateral ventricle. He also had nodular heterotopia, suggesting unilateral megalencephaly. CONCLUSION: Our study suggests that cerebellar cortical dysplasias are common in cases with more widespread cerebral malformations. Technical progress providing high-quality tridimensional MR imaging of the cerebellum may explain its recent descriptions.
机译：背景与目的：小脑皮质 发育不良的MR影像学表现被描述为一种新的小脑畸形。 该研究的目的是评估小脑 < / sup>皮质发育异常并伴有其他脑畸形。 方法：我们回顾性分析了46例患者 表现为发育迟缓，肌张力低下和面部畸形的MR检查。 >以识别小脑叶或裂隙或两者均在小脑半球或ver部内，提示皮质发育异常。 结果：1​​7例小脑皮质发育不良被诊断出。 有两名患者被隔离。在其余15例患者中， 畸形与Vermian畸形（n = 11）， 脑皮质发育异常（n = 8），call体发育异常 < / sup>（n = 6）和异位症（n = 5）。在八名患者中发现了 后颅窝的广泛畸形（Dandy-Walker， Chiari II和III，以及脑干发育不全）。小脑肥大半球的 患者右脑半球和侧脑室有较小的 。他还 患有结节性异位症，提示单侧巨脑畸形。 结论：我们的研究表明，小脑皮质发育异常 在脑畸形更为广泛的情况下很常见。 提供高质量的小脑三维MR 成像的技术进步可能会解释其最近的描述。

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  • 来源
    《American Journal of Neuroradiology》 |2000年第8期|1511-1519|共9页
  • 作者

    Gustavo Soto-Ares; Christine Delmaire; Berengere Deries; Louis Vallee; Jean Pierre Pruvo;

  • 作者单位

    From the Departments of Neuroradiology (G.S-A., C.D., B.D., J.P.P.) and Pediatric Neurology (L.V.), H?pital Roger Salengro, Chru Lille France.;

    From the Departments of Neuroradiology (G.S-A., C.D., B.D., J.P.P.) and Pediatric Neurology (L.V.), H?pital Roger Salengro, Chru Lille France.;

    From the Departments of Neuroradiology (G.S-A., C.D., B.D., J.P.P.) and Pediatric Neurology (L.V.), H?pital Roger Salengro, Chru Lille France.;

    From the Departments of Neuroradiology (G.S-A., C.D., B.D., J.P.P.) and Pediatric Neurology (L.V.), H?pital Roger Salengro, Chru Lille France.;

    From the Departments of Neuroradiology (G.S-A., C.D., B.D., J.P.P.) and Pediatric Neurology (L.V.), H?pital Roger Salengro, Chru Lille France.;

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