Gene Editing and the War Against Malaria

Ethan Bier; Elliott Sober

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Gene Editing and the War Against Malaria

机译：基因编辑和对疟疾的战争

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Malaria is a tropical illness that blood-feeding mosquitoes spread from person to person. In 2018, approximately 228 million malaria cases emerged, with an estimated 405,000 deaths recorded in the same period. More than half of those deaths were young children. Mosquito nets have limited effectiveness in preventing infection, as do pesticides, and antimalarial drugs also have limited effectiveness in preventing and treating infection (see figure on page 164). Compounding this problem is the lack of resources and infrastructure in regions where the risk for malaria is greatest.

机译：疟疾是一种热带疾病，使血液喂养的蚊子从人蔓延到人。 2018年，出现了大约2.28亿款疟疾案件，估计在同一时期记录了405,000人死亡。超过一半的死亡是幼儿。蚊帐在预防感染的有效性有限，杀虫剂和抗疟药药物在预防和治疗感染方面也具有有限的有效性（见第164页的图。复杂这个问题是患有疟疾风险最大的地区的资源和基础设施缺乏资源和基础设施。

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《American Scientist》 |2020年第3期|162-169|共8页
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Ethan Bier; Elliott Sober;
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收录信息美国《科学引文索引》(SCI);
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1. Archaeology of Colonial Pensacola – Edited by Judith A. Bense; Presidio Santa Maria de Galve: a struggle for survival in colonial Spanish Pensacola – Edited by Judith A. Bense; The Log of HMS Mentor, 1780–1781: a new account of the British Navy at Pensacola – Edited by James A. Servies; Pensacola during the Civil War: a thorn in the side of the Confederate – By George F. Pearce [J] . ANDREW LAMBERT International Journal of Nautical Archaeology . 2011,第2期

机译：彭萨科拉殖民地考古学–朱迪思·本斯（Judith A. Bense）编辑；圣玛丽亚·德·加尔维大街（Presidio Santa Maria de Galve）：西班牙殖民时期的彭萨科拉（Pensacola）求生存的斗争–朱迪思·本斯（Judith A. Bense）编辑HMS导师日志，1780–1781年：英国海军在彭萨科拉的新记述-詹姆斯·A·瑟维斯（James A. Servies）编辑；内战期间的彭萨科拉：同盟国的荆棘–乔治·皮尔斯（George F. Pearce）
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机译：第二次世界大战中的外科手术。胸外科手术-第I卷，医学博士Frank B. Berry编辑;副编辑，伊丽莎白·麦克菲特里奇（MA）与其他七个贡献者。在美国陆军外科医生伦纳德·希顿中将的指导下编写和出版。主编约翰·博伊德·科茨（John Boyd Coates）上校，美国马萨诸塞州，六月10x7？ in。Pp。 xxiv + 394，含70个数字。指数。 1963年。华盛顿：文件总监，美国政府印刷局，华盛顿特区，价格$ 4.25
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机译：第二次世界大战手术。神经外科。第II卷。由R. Glen Spurling，M.D.和Barnes Woodhall，M.D的编辑编辑。，其他贡献者。在美国陆军外科医生的主要一般S. Hays的方向下准备和公布。主编：John Boyd Coate，Jun。，M.C。 10 x 7？在。pp。 XXVI + 705，有286个数字（一些颜色）和许多表格。指数。 1959年。华盛顿：文件的主管，美国政府印刷办公室，华盛顿25，D.C.价格700美元
4. CoVim+CoEmacs: A Heterogeneous Co-editing System as a Potential Solution to Editor War [C] . Bryden Cho, Agustina Ng, Chengzheng Sun International conference on cooperative Design, visualization, and engineering . 2018

机译：CoVim + CoEmacs：异构共编辑系统，可作为编辑之战的潜在解决方案
5. Biomarkers of severe malaria: Complement activation and dysregulated angiogenesis in placental malaria and cerebral malaria [D] . Conroy, Andrea 2011

机译：严重疟疾的生物标志物：胎盘疟疾和脑疟疾中的补体激活和血管生成失调
6. Cas9-Mediated Gene-Editing in the Malaria Mosquito Anopheles stephensi by ReMOT Control [O] . Vanessa M. Macias, Sage McKeand, Duverney Chaverra-Rodriguez, 2020

机译：通过远程控制在疟原虫中的Cas9介导的基因编辑
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Gene Editing and the War Against Malaria

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