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Lingering Resistance

机译:持久的抵抗

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For bacteria, antibiotic resistance often comes at a cost, making cells less fit in other ways. In the absence of the drugs, natural selection should eliminate such costly resistance genes. But it's not that easy. On a farm that had been antibiotic free for two and a half years, researchers sampled gut bacteria from the feces of 10 hogs whose mother had also grown up antibiotic free. By the time the pigs reached slaughtering age, 69 percent of males' gut flora and 100 percent of females' were resistant to the common antibiotic chlor-tetracycline. Some resistance genes may persist because they're physically linked to genes that help microbes cope with metals in swine feed. The consequences for human health are unknown, but the results suggest that combating antibiotic resistance will take time.
机译:对于细菌而言,抗生素抗性通常是要付出代价的,这会使细胞无法通过其他方式适应。在没有药物的情况下,自然选择应该消除这种昂贵的抗性基因。但这不是那么容易。在一个有两年半无抗生素的农场,研究人员从10只猪的粪便中取样了肠道细菌,这些猪的母亲也长大了无抗生素。到猪达到屠宰年龄时,雄性肠道菌群中有69%的雌性肠道菌群对普通抗生素氯四环素具有抗性。一些抗性基因可能会持续存在,因为它们与帮助微生物应对猪饲料中金属的基因物理相连。对人类健康的后果尚不清楚,但结果表明,对抗抗生素耐药性需要时间。

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    《American Scientist》 |2012年第2期|p.123|共1页
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  • 收录信息 美国《科学引文索引》(SCI);
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  • 正文语种 eng
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