When PPLO Became Mycoplasma

Harold J. Morowitz

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When PPLO Became Mycoplasma

机译：PPLO成为支原体时

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Now that Craig Venter, Hamilton Smith and Clyde Hutchison, visionaries in the attempt to synthesize a living cell, have created three species of mycoplasma into landmarks on the road to their ambitious goal, mycoplasmas have become a favorite taxon in the popular press and the world of futuristic biology. When I first encountered these organisms they were known as pleuropneu-monia-like organisms-PPLOs-and few dreamed of the glory that lay ahead for this enigmatic group. How did these obscure microbes became important, indeed central, in understanding what it takes to be a living organism? The story will be told from an idiosyncratic and personal point of view-the view from my bench over five decades-and will show how mycoplasma instructed-and deceived-us about the nature of life.

机译：如今，有远见卓识的克雷格·文特（Craig Venter），汉密尔顿·史密斯（Hamilton Smith）和克莱德·哈奇森（Clyde Hutchison）在试图合成活细胞的过程中，已经将3种支原体创造成为实现其宏伟目标的里程碑，支原体已成为大众媒体和世界上最受欢迎的分类单元未来生物学。当我第一次遇到这些生物时，它们被称为胸膜肺炎样生物-PPLO，很少有人梦到这个神秘集团的荣耀。这些晦涩的微生物如何在理解成为活生物体的过程中变得非常重要，甚至变得至关重要呢？这个故事将以一种特质和个人的观点来讲述-我在过去的五十年中的观点-并将展示支原体如何指导和欺骗我们关于生命本质的知识。

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《American Scientist》 |2011年第2期|p.102-105|共4页
作者
Harold J. Morowitz;
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作者单位

Biology and Natural Philosophy at the Krasnow Institute of George Mason University Mail Stop 2A1, Fairfax, VA 22030;

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收录信息美国《科学引文索引》(SCI);
原文格式 PDF
正文语种 eng
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1. Mycoplasma meleagridis ("N" strain mycoplasma--PPLO): relationship of air sac lesions and isolations in day old turkeys (Meleagridis gallopavo). [J] . M L Benson, C H Bigland The Canadian veterinary journal . 1968,第6期

机译：meleagridis支原体（“ N”支原体-PPLO菌株）：日龄火鸡（Meleagridis gallopavo）中气囊损伤与分离的关系。
2. Evaluation of PPLO, A7B, E, and NYC agar media for the isolation of Ureaplasma urealyticum and Mycoplasma species from the genital tract. [J] . D M Yajko, E Balston, D Wood, Journal of Clinical Microbiology . 1984,第1期

机译：对PPLO，A7B，E和NYC琼脂培养基从生殖道中分离解脲脲原体和支原体物种的评估。
3. PRIMARY ISOLATION OF MYCOPLASMA ORGANISMS (PPLO) FROM MAMMALIAN SOURCES [J] . T. L. Barber, J. Fabricant Journal of bacteriology . 1962,第6期

机译：哺乳动物来源的霉菌（PPLO）的初步分离
4. EVALUATION OF A NEW MYCOPLASMA HYOPNEUMONIAE (M.hyo) BACTERIN TO CONTROL MYCOPLASMA PNEUMONIA IN PIGS EXPERIMENTALLY COINFECTED WITH PRRSV AND MYCOPLASMA HYPNEUMONIAE [C] . E .Thacker, D. Nilubol, R. Evans Congress ofthe International Pig Veterinary Society . 2008

机译：评估新的支原体纵向藓（M.Hyo）细菌在用PRRSV和支原体缺血试验繁殖的猪中测定猪的支原体肺炎
5. Exploring the Cell Surface: Identification and Characterization of Lipoproteins in Mycoplasma mycoides subsp. mycoides Large Colony, Mycoplasma mycoides subsp. capri, and Mycoplasma capricolum subsp. capricolum [D] . Martin, Tara R. 2009

机译：探索细胞表面：支原体支原体亚种中脂蛋白的鉴定和表征。大菌落，支原体亚种。卡普里岛和支原体亚种。癸酸
6. Mycoplasma meleagridis (N strain mycoplasma--PPLO): relationship of air sac lesions and isolations in day old turkeys (Meleagridis gallopavo). [O] . C H Bigland, M L Benson 1968

机译：meleagridis支原体（ N支原体-PPLO菌株）：日龄火鸡（Meleagridis gallopavo）中气囊损伤与分离的关系。
7. STUDIES OF PPLO INFECTION : I. THE PRODUCTION OF CEREBRAL POLYARTERITIS BY MYCOPLASMA GALLISEPTICUM IN TURKEYS; THE NEUROTOXIC PROPERTY OF THE MYCOPLASMA [O] . Thomas, Lewis, Davidson, Morton, McCluskey, Robert T. 1966

机译：PPLO感染的研究：I.盖氏白斑霉菌在土耳其产生的脑多动脉炎；骨髓炎的神经氧化特性
8. Association of Mycoplasma and Human Immunodeficiency Virus Infection: Detectionof Amplified Mycoplasma Fermentans DNA in Blood [R] . Hawkins, R. E., Rickman, L. S., Vermund, S. H., 1992

机译：支原体与人类免疫缺陷病毒感染的关联：血液中放大的支原体发酵DNa的检测

When PPLO Became Mycoplasma

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