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首页> 外文期刊>Annals of Nuclear Medicine >Central photopenic lesions on FDG-PET scan in a patient with peripheral T cell lymphoma
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Central photopenic lesions on FDG-PET scan in a patient with peripheral T cell lymphoma

机译：外周血T细胞淋巴瘤患者FDG-PET扫描的中央光瞳损伤

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摘要

Central necrosis in lymphoma lesions as demonstrated in [18F] fluoro-2-deoxyglucose positron emission tomography (FDG-PET) studies is a rare phenomenon, and the clinical significance of this observation has not been described in the literature. The role of FDG-PET in the management of peripheral T cell lymphoma (PTCL) is also still unclear at this time. We present a case of a patient newly diagnosed with PTCL who underwent both computed tomography (CT) and FDG-PET examinations prior to and following therapy. CT showed pulmonary cavitary lesions in both lungs, and PET demonstrated multiple large confluent masses with intense FDG uptake in the corresponding lung fields with central photopenia suggestive of necrosis. Post-treatment FDG-PET images showed a significant improvement in the previously described lesions with some residual, recurrent, and new lesions. Central necrosis shown by PET may be associated with the advanced stage of the disease and may have prognostic implications because of central necrosis caused by hypoxia.
机译：[18 F]氟-2-脱氧葡萄糖正电子发射断层扫描（FDG-PET）研究表明，淋巴瘤病变的中央坏死是一种罕见现象，该观察的临床意义尚未在文献中描述。目前，尚不清楚FDG-PET在外周T细胞淋巴瘤（PTCL）处理中的作用。我们介绍了一个新诊断为PTCL的患者，该患者在治疗前后均接受了计算机断层扫描（CT）和FDG-PET检查。 CT显示两个肺部都有肺空洞病变，PET显示相应肺野中有多个较大的融合块，FDG摄取旺盛，中央性低碳血症提示坏死。治疗后的FDG-PET图像显示，上述病变明显改善，并伴有一些残留，复发和新病变。 PET显示的中枢坏死可能与疾病的晚期有关，并且由于缺氧引起的中枢坏死可能具有预后意义。

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  • 来源
    《Annals of Nuclear Medicine》 |2008年第7期|629-633|共5页
  • 作者

    Ayse Mavi; Thiruvenkatasamy Dhuriraj; Tevfik F. Cermik; Muammer Urhan; Mariusz Wasik; Sandip Basu; Rakesh Kumar; Drew Torigian; Abass Alavi;

  • 作者单位

    Division of Nuclear Medicine Hospital of the University of Pennsylvania 3400 Spruce Street 110 Donner Bldg. Philadelphia PA 19104 USA;

    Division of Nuclear Medicine Hospital of the University of Pennsylvania 3400 Spruce Street 110 Donner Bldg. Philadelphia PA 19104 USA;

    Division of Nuclear Medicine Hospital of the University of Pennsylvania 3400 Spruce Street 110 Donner Bldg. Philadelphia PA 19104 USA;

    Division of Nuclear Medicine Hospital of the University of Pennsylvania 3400 Spruce Street 110 Donner Bldg. Philadelphia PA 19104 USA;

    Division of Nuclear Medicine Hospital of the University of Pennsylvania 3400 Spruce Street 110 Donner Bldg. Philadelphia PA 19104 USA;

    Division of Nuclear Medicine Hospital of the University of Pennsylvania 3400 Spruce Street 110 Donner Bldg. Philadelphia PA 19104 USA;

    Division of Nuclear Medicine Hospital of the University of Pennsylvania 3400 Spruce Street 110 Donner Bldg. Philadelphia PA 19104 USA;

    Division of Nuclear Medicine Hospital of the University of Pennsylvania 3400 Spruce Street 110 Donner Bldg. Philadelphia PA 19104 USA;

    Division of Nuclear Medicine Hospital of the University of Pennsylvania 3400 Spruce Street 110 Donner Bldg. Philadelphia PA 19104 USA;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    Peripheral T cell lymphoma; FDG-PET; Central necrosis; Hypoxia;

    机译：外周T细胞淋巴瘤;FDG-PET;中央坏死;缺氧;

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