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首页> 外文期刊>Annals of the New York Academy of Sciences >A unique vaccine for control of fertility and therapy of advanced-stage terminal cancers ectopically expressing human chorionic gonadotropin
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A unique vaccine for control of fertility and therapy of advanced-stage terminal cancers ectopically expressing human chorionic gonadotropin

机译:一种独特的控制生育力和异位表达人绒毛膜促性腺激素的晚期晚期癌症的疗法的疫苗

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摘要

Human chorionic gonadotropin (hCG) appears soon after fertilization of the egg and plays a critical role in implantation of the embryo leading to the beginning of pregnancy. Vaccines developed against hCG prevent pregnancy without impairment of ovulation and disturbance of menstrual regularity. A new recombinant vaccine hCGβ-LTB has been developed that is highly immunogenic in various strains of mice and intended for the control of fertility in women. An additional use of this vaccine is likely to be treatment of advanced-stage cancers that ectopically express hCG.
机译:人绒毛膜促性腺激素(hCG)在卵受精后不久出现,并在导致怀孕开始的胚胎植入中起关键作用。针对人绒毛膜促性腺激素(hCG)开发的疫苗可预防妊娠,而不会损害排卵和月经不调。已经开发了一种新的重组疫苗hCGβ-LTB,该疫苗在多种小鼠品系中具有高度免疫原性,旨在控制妇女的生育能力。该疫苗的其他用途可能是治疗异位表达hCG的晚期癌症。

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