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首页> 外文期刊>Annals of the New York Academy of Sciences >Do we understand the pathophysiology of GERD after sleeve gastrectomy?
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Do we understand the pathophysiology of GERD after sleeve gastrectomy?

机译：我们是否了解套筒胃切除后GERD的病理生理学？

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摘要

Gastroesophageal reflux disease (GERD), a prevalent problem among obese individuals, is strongly associated with obesity and weight loss. Hence, bariatric surgery effectively improves GERD for many patients. Depending on the type of bariatric procedure, however, surgery can also worsen or even cause a new onset of GERD. As a consequence, GERD remains a relevant problem for many bariatric patients, and especially those who have undergone sleeve gastrectomy (SG). Affected patients report not only a decrease in physical functioning but also suffer from mental and emotional problems, resulting in poorer social functioning. The pathomechanism of GERD after SG is most likely multifactorial and triggered by the interaction of anatomical, physiological, and physical factors. Contributing factors include the shape of the sleeve, the extent of injury to the lower esophageal sphincter, and the presence of hiatal hernia. In order to successfully treat post-sleeve gastrectomy GERD, the cause of the problem must first be identified. Therapeutic approaches include lifestyle changes, medication, interventional treatment, and/or revisional surgery.
机译：胃食管反流疾病（GERD），肥胖个体中的普遍存在问题，与肥胖和减肥密切相关。因此，肥胖症手术有效改善了许多患者的GERD。然而，根据肥胖症的类型，手术也可以恶化或甚至导致GERD的新发起。因此，GERD仍然是许多肥胖症患者的相关问题，特别是那些经过套管胃切除术（SG）的问题。受影响的患者不仅报告物理运作的减少，而且遭受精神和情绪问题，导致社会运作较差。 SG后GERD的土程机制很可能是多因素，并通过解剖学，生理和物理因素的相互作用引发。贡献因子包括套筒的形状，损伤程度较低的食管括约肌，以及疝疝的存在。为了成功地治疗后袖胃切除术，必须首先识别问题的原因。治疗方法包括生活方式改变，药物，介入治疗和/或常规手术。

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