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首页> 外文期刊>Apoptosis >Conversation between apoptosis and autophagy: “Is it your turn or mine?”
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Conversation between apoptosis and autophagy: “Is it your turn or mine?”

机译:凋亡与自噬之间的对话:“是你该死还是我?”

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摘要

Drug resistance of cancer cells is often correlated with apoptosis evasion; however, an active involvement of autophagy in this scenario has been recently proposed, based on the evidence that autophagy could exert a protective role toward the activation of apoptosis in cancer cells. In this review, we briefly review the basic features of apoptosis, and we describe in details the molecular patterns of autophagy, with a special emphasis on its still controversial physiological function(s). The crucial factors governing the cross talk between autophagy and apoptosis will be illustrated.
机译:癌细胞的耐药性通常与细胞凋亡逃避有关。然而,基于自噬可以对癌细胞凋亡激活起保护作用的证据,最近提出了自噬在这种情况下的积极参与。在这篇综述中,我们简要回顾了细胞凋亡的基本特征,并详细描述了自噬的分子模式,并特别强调了其仍存在争议的生理功能。将说明控制自噬和凋亡之间相互影响的关键因素。

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