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Rapid concentration of particle and bioparticle suspension based on surface acoustic wave

机译:基于表面声波的粒子和生物粒子悬浮液的快速浓缩

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摘要

A method of rapid particle concentration in a droplet has been developed using surface acoustic wave (SAW) technology. A droplet was partially placed on a surface acoustic wave propagation path, and particles were concentrated at the center of the droplet due to the asymmetry. The device consists of two IDTs and two reflectors. The one IDT is used for generating SAW and the opposite IDT is used for detecting output voltage signal amplitude, and then for calculating acoustic power density of a droplet. To investigate concentration effect of the device, starch suspension and rabbit blood cells were used in this paper. Different acoustic power density was applied ranging from 6.13 mw mm~(-2) to 210.9 mw mm~(-2). The concentration process occurs within 15 s under appropriate acoustic power density put on the droplet, which is much faster than currently available particle concentration mechanisms, and the method is also efficient, which concentrating the particles into an aggregate about one-fifth the size of the original droplet. Additional, the concentration process is no damage to bioparticles. This concentration method can improve greatly SAW biosensor system sensitivity.
机译:已经使用表面声波(SAW)技术开发了一种在液滴中快速浓缩粒子的方法。将液滴部分地放置在声表面波传播路径上,并且由于不对称性,粒子集中在液滴的中心。该设备由两个IDT和两个反射器组成。一个IDT用于生成SAW,而另一个IDT用于检测输出电压信号幅度,然后用于计算液滴的声功率密度。为了研究该装置的浓缩效果,本文使用了淀粉悬浮液和兔血细胞。施加了从6.13 mw mm〜(-2)到210.9 mw mm〜(-2)的不同声功率密度。在液滴上施加适当的声功率密度后,浓缩过程会在15 s内发生,这比目前可用的粒子浓缩机制要快得多,而且该方法也很有效,可以将粒子浓缩为约五分之一大小的聚集体。原始液滴。另外,浓缩过程不会损坏生物颗粒。这种浓缩方法可以大大提高声表面波生物传感器系统的灵敏度。

著录项

  • 来源
    《Applied Acoustics》 |2009年第8期|1137-1142|共6页
  • 作者单位

    Department of Electronic Information Science and Technology, Ningbo University, No. 818 FengHua Road, Zhejiang Province, Ningbo 315211, PR China;

    Department of Electronic Information Science and Technology, Ningbo University, No. 818 FengHua Road, Zhejiang Province, Ningbo 315211, PR China;

    Department of Electronic Information Science and Technology, Ningbo University, No. 818 FengHua Road, Zhejiang Province, Ningbo 315211, PR China;

    Department of Electronic Information Science and Technology, Ningbo University, No. 818 FengHua Road, Zhejiang Province, Ningbo 315211, PR China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    surface acoustic wave; particle concentration; interdigital transducer; droplet;

    机译:表面声波颗粒浓度叉指换能器水滴;

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