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首页> 外文期刊>Applied Mathematical Modelling >Determination of the thermo-physical properties of multi-layered biological tissues
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Determination of the thermo-physical properties of multi-layered biological tissues

机译：多层生物组织的热物理性质的测定

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摘要

Abnormal biological tissues possess unknown properties that must be estimated in order to decide the appropriate method of treatment in terms of amount of dosage and appropriate place of inoculation. The current work numerically investigates, for the first time, the simultaneous estimation of several thermo-physical properties of multi-layered tissues from internal temperature measurements. The heat propagation within the tissues is modelled by the thermal-wave model of bio-heat transfer, accounting for the finite speed of heat propagation. On the skin surface, a convective boundary condition holds taking into account the heat exchange with the environment, whilst on the most inner wall of the tissues a Dirichlet boundary temperature condition is prescribed. Accurate and stable reconstruction of the piecewise constant properties given by the thermal conductivity, heat capacity and blood perfusion rate is successfully achieved for two physical examples concerning three- and four-layered, one-dimensional tissues, subjected to externally induced aggression.
机译：异常的生物组织具有必须估计的未知特性，以便在剂量和适当的接种地点决定适当的治疗方法。目前在数值上对来自内部温度测量的多层组织的多个热物理性质同时进行数值研究。组织内的热传播由生物传热的热波模型进行建模，占热传播的有限速度。在皮肤表面上，对流边界条件表考虑到环境的热交换，而在组织的大多数内壁上规定了小侧面边界温度条件。对于三个和四层一维组织的两个物理示例，成功地实现了由导热率，热容量和血液灌注速率的分段恒定性能的准确和稳定的重建。

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  • 来源
    《Applied Mathematical Modelling》 |2021年第11期|228-242|共15页
  • 作者

    M. Alosaimi; D. Lesnic; J. Niesen;

  • 作者单位

    Department of Applied Mathematics University of Leeds Leeds LS2 9JT UK Department of Mathematics and Statistics College of Science Taif University P.O. Box 11099 Taif 21944 Saudi Arabia;

    Department of Applied Mathematics University of Leeds Leeds LS2 9JT UK;

    Department of Applied Mathematics University of Leeds Leeds LS2 9JT UK;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Inverse problem; Bio-heat transfer; Thermal-wave model; Stratified tissue;

    机译：反问题;生物传热;热波模型;分层组织;

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