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Anaerobic sugar catabolism in Lactococcus lactis: genetic regulation and enzyme control over pathway flux

机译:乳酸乳球菌的无氧糖分解代谢:途径通量的遗传调控和酶控制

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摘要

Lactic acid bacteria and particularly Lactococcus lactis are widely used for the production of lactic acid in fermented foods. Control of the catabolic rate in L. lactis, i.e., the rate of lactic acid production, appears to be determinant for dairy product quality. While the mechanisms involved in control have not been totally elucidated, they seem to depend upon the strain and the growth conditions. Furthermore, it remains unclear whether the catabolic rate is controlled at the level of transcription, translation or enzyme activity. The recent sequencing of the L. lactis genome has brought novel insights to physiologic studies of the bacteria. This review discusses both genetic information and metabolic studies concerning anaerobic sugar catabolism in L. lactis.
机译:乳酸菌,尤其是乳酸乳球菌被广泛用于发酵食品中的乳酸生产。乳酸乳球菌分解代谢速率的控制,即乳酸的产生速率,似乎决定了乳制品的质量。虽然尚未完全阐明控制的机制,但它们似乎取决于菌株和生长条件。此外,尚不清楚分解代谢速率是否控制在转录,翻译或酶活性水平。乳酸乳球菌基因组的最新测序为细菌的生理研究带来了新的见解。这篇综述讨论了关于乳酸乳球菌厌氧糖分解代谢的遗传信息和代谢研究。

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  • 来源
    《Applied Microbiology and Biotechnology》 |2002年第2期|24-32|共9页
  • 作者单位

    Laboratoire Biotechnologie Bioprocédés UMR 5504 INSA/CNRS and UMR 792 INSA/INRA Centre de Bioingénierie Gilbert Durand Institut National des Sciences Appliquées 31077 Toulouse Cedex 4 France;

    Laboratoire Biotechnologie Bioprocédés UMR 5504 INSA/CNRS and UMR 792 INSA/INRA Centre de Bioingénierie Gilbert Durand Institut National des Sciences Appliquées 31077 Toulouse Cedex 4 France;

    Laboratoire Biotechnologie Bioprocédés UMR 5504 INSA/CNRS and UMR 792 INSA/INRA Centre de Bioingénierie Gilbert Durand Institut National des Sciences Appliquées 31077 Toulouse Cedex 4 France;

    Laboratoire Biotechnologie Bioprocédés UMR 5504 INSA/CNRS and UMR 792 INSA/INRA Centre de Bioingénierie Gilbert Durand Institut National des Sciences Appliquées 31077 Toulouse Cedex 4 France;

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