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首页> 外文期刊>Applied psychophysiology and biofeedback >Cortisol, Health, and Coping in Patients with Nonspecific Low Back Pain
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Cortisol, Health, and Coping in Patients with Nonspecific Low Back Pain

机译：非特异性下腰痛患者的皮质醇，健康状况和应对方法

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摘要

Subjective health complaints (SHC), including nonspecific low back pain (LBP) as the most common single complaint, are the main reasons for long-term sick leave in many western countries. These complaints are often attributed to "stress". Cortisol has frequently been considered a biomarker reflecting sustained physiological HPA-axis activity, and is characterized by a high cortisol awakening response (CAR) and low evening values. The aim of the study was to investigate whether LBP patients had a normal characteristic cortisol profile, and whether possible deviations were related to coping and health. 305 patients on long-term sick leave for LBP participated in the study, and saliva cortisol profiles were compared to a reference population consisting of Danish workers. Cortisol was measured upon awakening, after 30 min, and in the evening. Additionally, patients answered questionnaires about SHC, fatigue, pain, coping, and social support. The patients showed a seemingly normal cortisol profile. However, CAR was larger among patients compared to the reference population. Patients with low cortisol reactivity had more SHC, pain, and fatigue, and those with higher evening cortisol reported higher scores on coping. The results are discussed in terms of theory, practical considerations, and possible mechanisms for the association between cortisol, health, and coping.
机译：主观健康投诉（SHC），包括非特异性下背痛（LBP）是最常见的单一投诉，是许多西方国家长期请病假的主要原因。这些抱怨通常归因于“压力”。皮质醇经常被认为是反映持续的生理HPA轴活性的生物标志物，其特点是皮质醇唤醒反应（CAR）高，夜间值低。该研究的目的是调查LBP患者是否具有正常的皮质醇特征谱，以及可能的偏差是否与应对和健康有关。 305名因LBP享有长期病假的患者参加了研究，并将唾液皮质醇谱与由丹麦工人组成的参考人群进行了比较。醒来，30分钟后和傍晚测量皮质醇。此外，患者回答了有关SHC，疲劳，疼痛，应对和社会支持的问卷。患者表现出看似正常的皮质醇特征。但是，与参考人群相比，患者中的CAR更大。皮质醇反应性低的患者有更多的SHC，疼痛和疲劳，夜间皮质醇水平较高的患者在应对方面得分更高。从理论，实践考虑以及皮质醇，健康和应对之间的关​​联的可能机制方面讨论了结果。

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