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首页> 外文期刊>Applied psychophysiology and biofeedback >Self-perception And Experiential Schemata In The Addicted Brain
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Self-perception And Experiential Schemata In The Addicted Brain

机译：上瘾的大脑中的自我感知和体验图式

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This study investigated neurophysiological differences between recovering substance abusers (RSA) and controls while electroencephalogram (EEG) was continuously recorded during completion of a new assessment instrument. The participants consisted of 56 total subjects; 28 RSA and 28 non-clinical controls (C). The participants completed the self-perception and experiential schemata assessment (SPESA) and source localization was compared utilizing standardized low-resolution electromagnetic tomography (sLORETA). The data show significant differences between groups during both the assessment condition and baselines. A pattern of alpha activity as estimated by sLORETA was shown in the right amygdala, uncus, hippocampus, BA37, insular cortex and orbito-frontal regions during the SPESA condition. This activity possibly reflects a circuit related to negative perceptions of self formed in specific neural pathways. These pathways may be responsive to the alpha activity induced by many substances by bringing the brain into synchrony if only for a short time. In effect this may represent the euphoria described by substance abusers.
机译：这项研究调查了康复药物滥用者（RSA）和对照组之间的神经生理差异，同时在完成新的评估工具期间连续记录了脑电图（EEG）。参加者共56个科目； 28个RSA和28个非临床对照（C）。参与者完成了自我感知和经验图式评估（SPESA），并使用标准的低分辨率电磁层析成像（sLORETA）对源定位进行了比较。数据显示，在评估条件和基准期间，各组之间存在显着差异。在SPESA病情期间，右侧杏仁核，un骨，海马，BA37，岛状皮层和眶额区显示了sLORETA估计的α活性。这种活动可能反映出与在特定神经通路中形成的自我消极观念有关的电路。如果仅在短时间内使大脑同步，则这些途径可能对许多物质诱导的α活性有反应。实际上，这可能代表吸毒者描述的欣快感。

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