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Surface modification of polypropylene nonwoven fabrics via covalent immobilization of nonionic sugar-based surfactants

机译:通过共价固定非离子糖基表面活性剂对聚丙烯无纺布进行表面改性

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摘要

Amphiphilic N-alkyl-1-amino-l-deoxy-D-glucitol (C_nAG, n=8, 12) were successfully prepared. Polypropylene nonwoven fabrics (PP_(NWF)) were grafted with glycidyl methacrylate (GMA) via a technique of UV-induced graft polymerization combined with plasma pre-treatment, and then PP_(NWF)-g-GMA was used for the covalent immobilization of C_nAG. The surface graft polymerization was confirmed by ATR-FTIR and XPS, respectively. Effect of grafting parameters, e.g., acetone content, monomer concentration and UV irradiation time on the grafting density of GMA was investigated. And the hemocompatibility of the modified PP_(NWF) was evaluated by protein adsorption and platelet adhesion. It was founded that the C_nAG-modified substrates greatly suppressed protein adsorption and platelet adhesion compared with the native and pGMA-grafted PP_(NWF).
机译:成功制备了两亲性N-烷基-1-氨基-1-脱氧-D-葡萄糖醇(C_nAG,n = 8,12)。聚丙烯无纺布(PP_(NWF))通过紫外线诱导的接枝聚合结合等离子体预处理技术与甲基丙烯酸缩水甘油酯(GMA)接枝,然后将PP_(NWF)-g-GMA用于共价固定。 C_nAG。表面接枝聚合分别通过ATR-FTIR和XPS确认。研究了接枝参数(例如丙酮含量,单体浓度和紫外线照射时间)对GMA接枝密度的影响。并通过蛋白质吸附和血小板粘附评价了改性PP_(NWF)的血液相容性。发现与天然和pGMA接枝的PP_(NWF)相比,C_nAG修饰的底物极大地抑制了蛋白质的吸附和血小板粘附。

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