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首页> 外文期刊>Applied Surface Science >Functionalized ormosil scaffolds processed by direct laser polymerization for application in tissue engineering
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Functionalized ormosil scaffolds processed by direct laser polymerization for application in tissue engineering

机译：通过直接激光聚合加工的功能化ormosil支架，用于组织工程

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摘要

Synthesized N,N'-(methacryloyloxyethyl triehtoxy silyl propyl carbamoyl-oxyhexyl)-urea hybrid methacrylate was polymerized by direct laser polymerization using femtosecond laser pulses with the aim of using it for subsequent applications in tissue engineering. The as-obtained scaffolds were modified either by low pressure argon plasma treatment or by covering the structures with two different proteins (lysozyme, fibrinogen). For improved adhesion, the proteins were deposited by matrix assisted pulsed laser evaporation technique. The functionalized structures were tested in mouse fibroblasts culture and the cells morphology, proliferation, and attachment were analyzed.
机译：合成的N，N'-（甲基丙烯酰氧基乙基三乙氧基甲硅烷基丙基氨基甲酰基-氧基己基）-脲杂化甲基丙烯酸酯通过飞秒激光脉冲通过直接激光聚合进行聚合，目的是将其用于组织工程中的后续应用。通过低压氩等离子体处理或通过用两种不同的蛋白质（溶菌酶，纤维蛋白原）覆盖结构来修饰获得的支架。为了提高粘附力，通过基质辅助脉冲激光蒸发技术沉积蛋白质。在小鼠成纤维细胞培养物中测试了功能化结构，并分析了细胞形态，增殖和附着。

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  • 来源
    《Applied Surface Science》 |2013年第1期|357-361|共5页
  • 作者

    A. Matei; J.Schou; S.Canulescu; M.Zamfirescu; C Albu; B. Mitu; E.C.Buruiana; T. Buruiana; C. Mustaciosu; I. Petcu; M. Dinescu;

  • 作者单位

    Petru Poni Institute of Macromolecular Chemistry, Crigore Chica Voda41A, 6600 last Romania,National Institute for Lasers, Plasma and Radiation Physics, Atomistilor 409, 77125 Bucharest-Magurele, Romania;

    DTU Fotonik, Rise Campus, Technical University of Denmark, DK-4000 Roskilde, Denmark;

    DTU Fotonik, Rise Campus, Technical University of Denmark, DK-4000 Roskilde, Denmark;

    National Institute for Lasers, Plasma and Radiation Physics, Atomistilor 409, 77125 Bucharest-Magurele, Romania;

    National Institute for Lasers, Plasma and Radiation Physics, Atomistilor 409, 77125 Bucharest-Magurele, Romania;

    National Institute for Lasers, Plasma and Radiation Physics, Atomistilor 409, 77125 Bucharest-Magurele, Romania;

    Petru Poni Institute of Macromolecular Chemistry, Crigore Chica Voda41A, 6600 last Romania;

    Petru Poni Institute of Macromolecular Chemistry, Crigore Chica Voda41A, 6600 last Romania;

    Department of Environmental and Life Physics, National Institute for Physics and Nuclear Engineering 'Horia Hulubei', Bucharest, Romania;

    Department of Environmental and Life Physics, National Institute for Physics and Nuclear Engineering 'Horia Hulubei', Bucharest, Romania;

    Department of Environmental and Life Physics, National Institute for Physics and Nuclear Engineering 'Horia Hulubei', Bucharest, Romania;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    Ormosil scaffolds; Direct laser writing; Low pressure plasma treatment; MAPLE;

    机译：Ormosil脚手架;直接激光写入;低压等离子体处理;枫;

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