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首页> 外文期刊>Applied Surface Science >Preparation of fluoride substituted apatite cements as the building blocks for tooth enamel restoration
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Preparation of fluoride substituted apatite cements as the building blocks for tooth enamel restoration

机译：制备氟取代的磷灰石水泥作为牙釉质修复的基础

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摘要

Fluoride substituted apatite cement (fs-AC) was synthesized by using the cement powders of tetracal-cium phosphate (TTCP) and sodium fluoride (NaF), and the cement powders were mixed with diluted phosphoric acid (H_3PO_4) as cement liquid to form fs-AC paste. The fs-AC paste could be directly filled into the carious cavities to repair damaged dental enamel. The results indicated that the fs-AC paste was changed into fluorapatite crystals with the atom molar ratio for calcium to phosphorus of 1.66 and the F ion amount of 3 wt% after self-hardening for 2 days. The solubility of fs-AC in Tris-HC1 solution (pH 6) was slightly lower than hydroxyapatite cement (HAC) that was similar to the apatite in enamel, indicating the fs-AC was much insensitive to the weakly acidic solution than the apatite in enamel. The fs-AC was tightly combined with the enamel surface because of the chemical reaction between the fs-AC and the apatite in enamel after the caries cavities was filled with fs-AC. The extracts of fs-AC caused no cytotoxicity on L929 cells, which satisfied the relevant criterion on dental biomaterials, revealing good cytocompatibility. The fs-AC had potential prospect for the reconstitutkm of carious lesion of dental enamel.
机译：以磷酸四钙（TTCP）和氟化钠（NaF）的水泥粉为原料，合成了氟化物取代的磷灰石水泥（fs-AC），并将水泥粉与稀磷酸（H_3PO_4）混合作为水泥液形成fs。 -交流粘贴。可以将fs-AC糊剂直接填充到龋齿腔中，以修复受损的牙釉质。结果表明，自硬化2天后，fs-AC糊剂转变为氟磷灰石晶体，钙磷原子摩尔比为1.66，F离子含量为3 wt％。 fs-AC在Tris-HC1溶液（pH 6）中的溶解度略低于羟基磷灰石水泥（HAC），后者与搪瓷中的磷灰石相似，这表明fs-AC对弱酸性溶液的敏感性不如磷灰石中的磷灰石。搪瓷。 fs-AC与釉质表面紧密结合，这是因为龋齿腔中充满了fs-AC之后，fs-AC与搪瓷中的磷灰石之间发生了化学反应。 fs-AC提取物对L929细胞无细胞毒性，符合牙科生物材料相关标准，具有良好的细胞相容性。 fs-AC有望修复牙釉质的龋损。

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  • 来源
    《Applied Surface Science》 |2011年第17期|p.7887-7892|共6页
  • 作者

    Jie Wei; Jiecheng Wang; Xiaochen Liu; Jian Ma; Changsheng Liu; Jing Fang; Shicheng Wei;

  • 作者单位

    Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Inter-disciplinary Studies, Peking University, Beijing 100871 PR China,Key Laboratory for Ultrafine Materials of Ministry of Education, East China University of Science and Technology, Shanghai 200237, PR China;

    Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Inter-disciplinary Studies, Peking University, Beijing 100871 PR China;

    Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Inter-disciplinary Studies, Peking University, Beijing 100871 PR China;

    Hospital of Stomatology, Tongji University, Shanghai 200072, PR China;

    Key Laboratory for Ultrafine Materials of Ministry of Education, East China University of Science and Technology, Shanghai 200237, PR China;

    Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Inter-disciplinary Studies, Peking University, Beijing 100871 PR China;

    Center for Biomedical Materials and Tissue Engineering, Academy for Advanced Inter-disciplinary Studies, Peking University, Beijing 100871 PR China,School and Hospital of Stomatology, Peking University, Beijing 100081 PR China;

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  • 正文语种 eng
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  • 关键词

    dental enamel; carious cavities; fluorapatite cement; restoration; cytocompatibility;

    机译：牙釉质龋洞;氟磷灰石水泥;恢复;细胞相容性;

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