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Surface modification of PDMS using atmospheric glow discharge polymerization of tetrafluoroethane for immobilization of biomolecules

机译:使用四氟乙烷常压辉光放电聚合固定生物分子,对PDMS进行表面改性

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摘要

In this study an atmospheric glow discharge with a fluorocarbon gas as precursor was used to modify the surface of polydimethyl siloxane (PDMS -[(CH_3)2SiO]_n-). The variation in protein immobilizing capability of PDMS was studied for different times of exposure. It was observed that the concentration of proteins adsorbed on the surface varied in an irregular manner with treatment time. The fluorination results in the formation of a thin film of fluorocarbon on the PDMS surface. The AFM and XPS data suggest that the film cracks due to stress and regains its uniformity thereafter. This Stranski-Krastanov growth model of the film was due to the high growth rate offered by atmospheric glow discharge.
机译:在这项研究中,以碳氟化合物气体为前体的大气辉光放电被用于修饰聚二甲基硅氧烷(PDMS-[(CH_3)2SiO] _n-)的表面。研究了PDMS在不同暴露时间下蛋白质固定能力的变化。观察到,吸附在表面上的蛋白质的浓度随处理时间以不规则的方式变化。氟化导致在PDMS表面上形成碳氟化合物薄膜。 AFM和XPS数据表明,该膜由于应力而破裂,​​然后恢复其均匀性。薄膜的这种Stranski-Krastanov生长模型是由于大气辉光放电提供的高生长速率所致。

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  • 来源
    《Applied Surface Science》 |2011年第20期|p.8378-8384|共7页
  • 作者单位

    Plasma Process Laboratory, Department of Instrumentation and Applied Physics, Indian Institute of Science, Bangalore, 560012, India;

    Multidisciplinary and Multiscale Device and Design Laboratory (M2D2), Department of Mechanical Engineering, Indian Institute of Science, Bangalore, 560012, India;

    Plasma Process Laboratory, Department of Instrumentation and Applied Physics, Indian Institute of Science, Bangalore, 560012, India,Multidisciplinary and Multiscale Device and Design Laboratory (M2D2), Department of Mechanical Engineering, Indian Institute of Science, Bangalore, 560012, India;

    Plasma Process Laboratory, Department of Instrumentation and Applied Physics, Indian Institute of Science, Bangalore, 560012, India;

    Structure Function Analysis Lab, Department of Molecular Reproduction Development and Genetics, Indian Institute of Science, Bangalore, 560012, India;

    Structure Function Analysis Lab, Department of Molecular Reproduction Development and Genetics, Indian Institute of Science, Bangalore, 560012, India;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    APGD; PDMS; protein; surface modification; wettability;

    机译:APGD;PDMS;蛋白;表面改性;润湿性;

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