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Study On Surface Modification Of Porous Apatite-wollastonite Bioactive Glass Ceramic Scaffold

机译:多孔磷灰石-硅灰石生物活性玻璃陶瓷支架的表面改性研究

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Chitosan (CS) was used to modify the surface of apatite-wollastonite bioactive glass ceramic (AW GC) scaffold to prepare AW/CS composite scaffold. The in vitro bioactivity of the AW/CS composite scaffold was investigated by simulated body fluid (SBF) soaking experiment. Cell growth on the surface of the material was evaluated by co-culturing osteogenic marrow stromal cells (MSCs) of rabbits with the scaffold. The results showed that the compressive strength of AW GC scaffold was improved dramatically after being modified by CS, whereas the mineralization rate was delayed. MSCs can attach well on the surface of the composite scaffold.
机译:壳聚糖(CS)用于改性磷灰石-硅灰石生物活性玻璃陶瓷(AW GC)支架的表面,以制备AW / CS复合支架。通过模拟体液(SBF)浸泡实验研究了AW / CS复合支架的体外生物活性。通过将兔的成骨骨髓基质细胞(MSCs)与支架共同培养来评估材料表面的细胞生长。结果表明,CS改性后,AW气相色谱支架的抗压强度得到了显着提高,而矿化速率有所延迟。 MSC可以很好地附着在复合支架的表面上。

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