• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Applied Surface Science >Investigation of a biofunctional polymeric coating deposited onto silicon microcantilevers
【24h】

Investigation of a biofunctional polymeric coating deposited onto silicon microcantilevers

机译：沉积在硅微悬臂上的生物功能聚合物涂层的研究

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The paper deals with an appealing route to activate silicon microcantilevers (90,110 and 130 μm long, 35 μm wide and 2 μm thick) for specific binding of biochemical species. The method consists in coating the underivatized microcantilevers with a biofunctional copolymer (based on N,N-dimethylacrylamide bearing silanating moieties) that was developed for low-density microarray assays on microscope glass slides. Coating deposition was obtained by dip-coating' and its microstructure investigated by analyzing the resonance frequency values of bare and coated microcantilevers, by SEM and SFM imaging, SFM tip-scratch tests and XRR experiments. Results indicate that the coating is 2.5 nm thick and has a density of 1.22 g/cm~3. The coating surface is nanostructured, displaying nanoblobs, which are from few up to 20 nm wide and, on average, 1.6 nm high. The diameter of the biggest nanoblobs is of the same order of magnitude of the gyration radius of the copolymer chains, suggesting that nanoblobs may identify individual macromolecules.
机译：该论文提出了一条吸引人的途径来激活硅微悬臂梁（长90,110和130μm，宽35μm，厚2μm），以实现生物化学物质的特异性结合。该方法包括用生物功能共聚物（基于带有N，N-二甲基丙烯酰胺的硅烷化部分）涂覆未衍生化的微悬臂，该生物功能共聚物被开发用于显微镜载玻片上的低密度微阵列分析。通过浸涂获得涂层沉积，并通过SEM和SFM成像，SFM尖端刮擦试验和XRR实验分析裸露的和涂覆的微悬臂梁的共振频率值来研究其微结构。结果表明涂层为2.5nm厚，密度为1.22g / cm〜3。涂层表面是纳米结构的，显示出纳米气泡，其宽度从几纳米到20 nm，平均高1.6 nm。最大的纳米气泡的直径与共聚物链的回转半径的大小处于同一数量级，这表明纳米气泡可以识别单个大分子。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号