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Molecule specific imaging in biology: What are the challenges and the important applications?

机译:生物学中的分子特异性成像:挑战和重要应用是什么?

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It is becoming clear that mass spectrometry is a powerful tool for the analysis and imaging of complex organic and biological systems. The discussion session "Meeting the Challenge of Molecule Specific Analysis and Imaging in Organic and Bio-Systems" will attempt to illustrate the challenges to be met in mass spectral imaging and analysis of biological samples. Some of these challenges will be discussed here including the issues of sensitivity needed to obtain high resolution images at the cellular and sub-cellular level, information that can be obtained with alternative techniques and where will they be better versus when SIMS will be better suited to the need, and finally the need for depth profiling and mechanisms to achieve this goal for cellular samples. (c) 2006 Elsevier B.V. All rights reserved.
机译:显然,质谱仪是用于分析和成像复杂的有机和生物系统的强大工具。讨论会“应对有机和生物系统中的分子特异性分析和成像的挑战”将试图说明在质谱成像和生物样品分析中要面对的挑战。这里将讨论这些挑战中的一些挑战,包括在细胞和亚细胞水平上获得高分辨率图像所需的灵敏度问题,可以通过替代技术获得的信息以及与SIMS更适合于何时相比它们将在哪些方面变得更好最终需要进行深度分析,以及实现细胞样品这一目标的机制。 (c)2006 Elsevier B.V.保留所有权利。

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