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Polychlorinated biphenyls, mercury, and potential endocrine disruption in fish from the Hudson River, New York, USA

机译:美国纽约哈德逊河的鱼类中的多氯联苯,汞和潜在的内分泌干扰物

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Tissue residues of total mercury (Hg), total polychlorinated biphenyls (PCBs), and lipid-based PCBs; plasma concentrations of endocrine biomarkers; and reproductive and histologic biomarkers were assessed in 460 carp (Cyprinus carpio), bass (Micropterus salmoides and Micropterus dolomieui), and bullhead (Ameiurus nebulosus) collected from eight sites across the Hudson River Basin in the spring of 1998 to determine if endocrine disruption was evident in resident fish species and to evaluate contaminant-biomarker interrelations. Total PCBs in bed sediments (maximum 2,500 μg kg~(-1)) could explain 64 to 90% of the variability in lipid-based PCB residues in tissues (maximum 1,250 μg PCB g-lipid~(-1)) of the four species. The 17β-estradiol to 11-ke-totestosterone ratio, typically less than 1.0 in male fish and greater than 1.0 in females, exceeded 1.4 in all male largemouth bass and 35% of male carp and bullhead at one site 21 km downstream from a major PCB source. Endocrine biomarkers were significantly correlated with total Hg in female smallmouth bass and carp, and with lipid-based PCBs in males of all four species. Empirical evidence of endocrine modulation in blood plasma of male and female fish from sites with and without high PCB residues in bed sediments and fish tissues suggest that PCBs, Hg, or other contaminants may disrupt normal endocrine function in fish of the Hudson River.
机译:总汞(Hg),多氯联苯(PCB)和基于脂质的PCB的组织残留;内分泌生物标志物的血浆浓度;在1998年春季从哈德逊河流域的8个地点收集了460鲤(鲤),鲈鱼(Salmoides和细鳍螯虾)和bull鱼(Ameiurus nebulosus),并对其生殖和组织学生物标志物进行了评估,以确定是否破坏了内分泌在常驻鱼类中显而易见,并评估污染物与生物标志物的相互关系。床沉积物中的多氯联苯总量(最大2,500μgkg〜(-1))可以解释这四种组织中脂质基多氯联苯残留量(最大1,250μgPCB g-脂质〜(-1))的64%至90%。种类。 17β-雌二醇与11-ke-睾丸酮之比通常在雄性鱼类下游小于1 km的一个地方,雄鱼中小于1.0,雌性中大于1.0,所有雄性大嘴鲈均超过1.4,雄鲤和carp头的比例超过35%。 PCB源。内分泌生物标志物与雌性小嘴鲈鱼和鲤鱼中的总汞显着相关,并且与所有四个物种的雄性中基于脂质的PCBs显着相关。来自和没有河床沉积物和鱼组织中多氯联苯残留的部位的雄性和雌性鱼血浆中内分泌调节的经验证据表明,多氯联苯,汞或其他污染物可能会破坏哈德逊河鱼的正常内分泌功能。

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