Induction of endostatin expression in meniscal fibrochondrocytes by co-culture with endothelial cells

Maik Hoberg; Edda L. Schmidt; Melanie Tuerk; Viviane Stark; Wilhelm K. Aicher; Maximilian Rudert

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Induction of endostatin expression in meniscal fibrochondrocytes by co-culture with endothelial cells

机译：与内皮细胞共培养诱导内皮抑素在半月板软骨细胞中的表达

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Introduction The ultimate goal after meniscus damage is the preservation of the original meniscal tissue, which is often impossible due to the limited healing capacity of meniscal lesions, especially in the avascular zone. Factors produced by endothelial cells of meniscal vessels may contribute to better wound healing in vascularized zones. We therefore investigated the expression of different angiogenic factors, growth hormones and cytokines in human fibrochondrocytes and in fibrochondrocytes upon co-culture with endothelial cells, to examine mechanisms of repair of meniscal injury in more detail and to investigate the potential use of endothelial cells in co-cultures for autologous meniscal repair utilizing tissue engineering technology.

机译：简介半月板损伤后的最终目标是保留半月板原始组织，由于半月板病变的愈合能力有限，尤其是在无血管区，因此通常不可能做到这一点。半月板血管内皮细胞产生的因子可能有助于改善血管区域的伤口愈合。因此，我们研究了与内皮细胞共培养后，人纤维软骨细胞和纤维软骨细胞中不同血管生成因子，生长激素和细胞因子的表达，以更详细地研究半月板损伤的修复机制，并研究了内皮细胞在血管内皮细胞中的潜在用途。组织工程技术进行自体半月板修复的培养。

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《Archives of Orthopaedic and Trauma Surgery》 |2009年第8期|p.1137-1143|共7页
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Maik Hoberg; Edda L. Schmidt; Melanie Tuerk; Viviane Stark; Wilhelm K. Aicher; Maximilian Rudert;
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1. Induction of endostatin expression in meniscal fibrochondrocytes by co-culture with endothelial cells. [J] . Hoberg M, Schmidt EL, Tuerk M, Archives of orthopaedic and trauma surgery. . 2009,第8期

机译：通过与内皮细胞共培养来诱导内皮抑素在半月板软骨细胞中的表达。
2. Induction of EGFP expression in Pichia pastoris during co-culture with human endothelial cell line [J] . Thor Der, Xiao Nan, Yu Ryan, Journal of Microbiological Methods . 2019,第期

机译：在与人内皮细胞系共培养期间Pichia Pastoris中EGFP表达的诱导
3. Reciprocal induction of human dermal microvascular endothelial cells and human mesenchymal stem cells: Time-dependent profile in a co-culture system [J] . LaranjeiraM.S., FernandesM.H., MonteiroF.J. Cell Proliferation . 2012,第4期

机译：人类真皮微血管内皮细胞和人类间充质干细胞的相互诱导：共培养系统中的时间依赖性
4. Establishment of Vascular Networks in Biochips Using Co-cultures of Adipose Derived Stem Cells and Endothelial Cells in a 3D Fibrin Matrix [C] . Michaela Purtscher, Mario Rothbauer, Wolfgang Holnthoner International Federation for Medical and Biological Engineering European Conference . 2015

机译：使用脂肪衍生的干细胞和3D纤维蛋白基质内皮细胞的共培养，在生物芯片中建立血管网络
5. Fibrin induction of IL-8 expression in vascular endothelial cells [D] . Qi, Jiafan. 1994

机译：纤维蛋白诱导血管内皮细胞中IL-8表达
6. The effects of cetuximab alone and in combination with endostatin on vascular endothelial growth factor and interleukin-8 expression in human lung adenocarcinoma cells [O] . Yong-Feng Yu, Zhi-Wei Chen, Zi-Ming Li, 2009

机译：单独使用西妥昔单抗及与内皮抑素联合使用对人肺腺癌细胞中血管内皮生长因子和白细胞介素8表达的影响
7. 31.4 Induction of endostatin expression in mensical fibrochondrocyte by cocultur with endothelial cells [O] . Rudert M., Aicher W.K., Hoberg M. 2007

机译：31.4通过与内皮细胞共培养诱导内皮抑素在月经性线粒体细胞中的表达

Induction of endostatin expression in meniscal fibrochondrocytes by co-culture with endothelial cells

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