An oxepinoflavone from Artocarpus elasticus with cytotoxic activity against P-388 cells

Iqbal Musthapa; Lia D. Juliawaty; Yana M. Syah; Euis H. Hakim; Jalifah Latip; Emilio L. Ghisalberti

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An oxepinoflavone from Artocarpus elasticus with cytotoxic activity against P-388 cells

机译：松果皮中的氧杂松黄酮对P-388细胞具有细胞毒活性

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A new oxepinoflavone, artoindonesianin E1 (1), was isolated from the wood of Artocarpus elasticus, along with four known prenylated flavones: artocarpin (2), cycloartocarpin (3), cudraflavones A (4) and C (5). The structure of the new compound was identified by spectroscopic methods. Upon cytotoxic evaluation against murine leukemia P-388 cells, the new compound showed IC₅₀ 5.0 μg/mL.

机译：从松果木中分离出了一种新的氧杂品黄酮，青蒿素E1（1），以及四种已知的烯丙基黄酮：青蒿素（2），环artocarpin（3），草黄酮A（4）和C（5）。通过光谱法鉴定了新化合物的结构。经对鼠白血病P-388细胞的细胞毒性评估，新化合物显示IC _{50 5.0μg/ mL。}

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《Archives of Pharmacal Research》 |2009年第2期|p.191-194|共4页
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Iqbal Musthapa; Lia D. Juliawaty; Yana M. Syah; Euis H. Hakim; Jalifah Latip; Emilio L. Ghisalberti;
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1. An oxepinoflavone from Artocarpus elasticus with cytotoxic activity against P-388 cells. [J] . Musthapa I, Juliawaty LD, Syah YM, Archives of pharmacal research . 2009,第2期

机译：松果皮中的氧杂品黄酮对P-388细胞具有细胞毒活性。
2. Prenylated flavones from Artocarpus lanceifolius and their cytotoxic properties against P-388 cells [J] . Musthapa I., Latip J., Takayama H., Natural product communications . 2009,第7期

机译：面包果的异戊烯黄酮及其对P-388细胞的细胞毒性
3. Identification of Cytotoxic Compound from Artocarpus communis Leaves Against P-388 Cells [J] . Puspa D.N. Lotulung, Sofa Fajriah, Muhammad Hanafi, Pakistan Journal of Biological Sciences . 2008,第21期

机译：面包果叶片对P-388细胞的细胞毒性化合物的鉴定
4. A Flavone Derivative from Sesbania sesban Leaves and Its Cytotoxicity against Murine Leukemia P-388 Cells [C] . Hanhan Dianhar, Yana Maolana Syah, Didin Mujahidin, ICMNS 2012 . 2014

机译：来自Sesbania Sesban的黄酮衍生物叶和其对鼠白血病P-388细胞的细胞毒性
5. Structure-activity studies, role of transferrin, and gene expression profile of the cytotoxic activity of titanium(IV) complexes in colon adenocarcinoma HT29 cells. [D] . Hernandez Castillo, Ramon Luis. 2009

机译：结构活性研究，转铁蛋白的作用以及钛（IV）配合物在结肠腺癌HT29细胞中的细胞毒性活性的基因表达谱。
6. High In-Vitro Antitumour Activity of Triphenyltin Coumarin 3-Carboxylate and its Coordination Complexes With Monodentate Oxygen Donor Ligands Against the Epstein Barr Virus (EBV)-DNA Positive Raji and the P-388 Murine Leukaemia Cell Lines and Evidence for the Suppression by Organotin of the Early Antigen Complex in the EBV Lytic Cycle [O] . Joyce Koshy, V. G. Kumar Das, S. Balabaskaran, 2000

机译：三苯基锡香豆素3-羧酸及其与单齿供氧配体的配合物对爱泼斯坦巴尔病毒（EBV）-DNA阳性Raji和P-388鼠白血病细胞系的体外抗肿瘤活性高并被有机锡抑制EBV裂解周期中早期抗原复合物的合成
7. Cytotoxic Prenylflavonoids from Artocarpus elasticus [O] . -1

机译：来自Artocarpus弹性的细胞毒性戊糖酚

An oxepinoflavone from Artocarpus elasticus with cytotoxic activity against P-388 cells

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