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首页> 外文期刊>Asian Journal of Andrology >Gonadal damage and options for fertility preservation in female and male cancer survivors
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Gonadal damage and options for fertility preservation in female and male cancer survivors

机译：男性和女性癌症幸存者的性腺损害和保留生育能力的选择

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摘要

It is estimated that in 2010, 1 in every 250 adults will be a childhood cancer survivor. Today, oncological surgery, radiotherapy and chemotherapy achieve relatively high rates of remission and long-term survival, yet are often detrimental to fertility. Quality of life is increasingly important to long-term survivors of cancer, and one of the major quality-of-life issues is the ability to produce and raise normal children. Developments in the near future in the emerging field of fertility preservation in cancer survivors promise to be very exciting. This article reviews the published literature, discusses the effects of cancer treatment on fertility and presents the options available today thanks to advances in assisted-reproduction technology for maintaining fertility in male and female patients undergoing this type of treatment. The various diagnostic methods of assessing the fertility potential and the efficacy of in vitro fertilization (IVF) after cancer treatment are also presented.
机译：据估计，2010年，每250名成人中就有1名是儿童癌症幸存者。如今，肿瘤外科手术，放疗和化学疗法可达到较高的缓解率和长期生存率，但通常不利于生育。生活质量对癌症的长期幸存者而言越来越重要，主要的生活质量问题之一是能否养育和抚养正常的孩子。在不久的将来，癌症幸存者的生育力保存新兴领域的发展有望令人兴奋。本文回顾了已发表的文献，讨论了癌症治疗对生育力的影响，并介绍了由于辅助生殖技术在维持这种类型的男性和女性患者的生育力方面取得的进步而当今可用的选择。还介绍了各种诊断方法，这些方法可评估癌症治疗后的生育能力和体外受精（IVF）的功效。

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