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首页> 外文期刊>Atmospheric environment >Investigating the geographical heterogeneity in PM_(10)-mortality associations in the China Air Pollution and Health Effects Study (CAPES): A potential role of indoor exposure to PM_(10) of outdoor origin
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Investigating the geographical heterogeneity in PM_(10)-mortality associations in the China Air Pollution and Health Effects Study (CAPES): A potential role of indoor exposure to PM_(10) of outdoor origin

机译：在《中国空气污染与健康影响研究》（CAPES）中调查PM_（10）-死亡率关联中的地理异质性：室内暴露于室外PM_（10）的潜在作用

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This study gives the first-time evidence for China that the geographical heterogeneity of the acute effects of outdoor PM_(10) can be partially explained by differences in indoor exposure to PM_(10) of outdoor origin. We used data from the China Air Pollution and Health Effects Study (CAPES), which demonstrated a geographical heterogeneity of the acute effect of particulate air pollution (paniculate matter with an aerodynamic diameter smaller than 10 μm, or PM_(10)) on mortality in 16 Chinese cities. Given that a large fraction of the exposure to PM_(10) of outdoor origin occurs indoors, we made the hypothesis that this heterogeneity might be partially explained by inter-city differences in indoor exposure to PM_(10) of outdoor origin. In our analysis, we estimated PM_(10) exposure coefficients (the change in the estimated personal exposure to PM_(10) of outdoor origin per unit change in outdoor PM_(10) concentration) in these 16 Chinese cities and examined their correlation with PM_(10) mortality coefficients (the increase in mortality associated with a given increase in the concentrations of outdoor PM_(10)). We showed that the PM_(10) mortality coefficients and the PM_(10) exposure coefficients were significantly correlated, with an R-squared (R~2) value of 0.549 (95% confidence interval: 0.201, 0.771; p < 0.01) for the 16 cities. The correlation was robust with different values of the key input parameters, and close in value to estimations found in previous studies on similar subjects.
机译：这项研究为中国提供了首次证据，证明室外PM_（10）急性效应的地理异质性可以部分通过室内暴露于室外PM_（10）的差异来解释。我们使用了来自中国空气污染与健康影响研究（CAPES）的数据，该数据证明了颗粒空气污染（空气动力学直径小于10μm的颗粒物，或PM_（10））对动物死亡率的急性影响的地理异质性。中国的16个城市。假设大部分室外暴露于PM_（10）的暴露发生在室内，我们做出这样的假设，即这种异质性可能部分由室内暴露室外暴露于PM_（10）的城市间差异来解释。在我们的分析中，我们估算了这16个中国城市的PM_（10）暴露系数（单位室外PM_（10）浓度变化引起的个人暴露于室外PM_（10）的估计暴露量的变化），并检验了它们与PM_ （10）死亡率系数（与室外PM_（10）的给定增加相关的死亡率增加）。我们显示PM_（10）死亡率系数和PM_（10）暴露系数显着相关，R平方（R〜2）值为0.549（95％置信区间：0.201，0.771; p <0.01） 16个城市。在关键输入参数的不同值下，相关性很强，并且其值与先前对类似主题的研究中发现的估计值接近。

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