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The effects of vaccination in an age-dependent model for varicellaand herpes zoster

机译：水痘和带状疱疹的年龄依赖性模型中接种疫苗的影响

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The varicella-zoster virus (VZV) is responsible for the infectious diseases varicella and herpes zoster, more commonly known as chickenpox and shingles. The United States Food and Drug Administration recently approved a VZV vaccine for use in children to prevent chickenpox. The VZV vaccine was tested in Japan, Korea, and the United States, and these extensive experimental investigations led to final approval in the United States. In this paper, an age-dependent model for varicella and herpes zoster is formulated. Using statistics for the United States, parameter values for the model are estimated and numerical solutions are calculated. The effects of various control strategies, designed to decrease the number of individuals susceptible to varicella and zoster, are investigated. In particular, the effect of vaccination on the average age of infection, the average number of infections per person during their lifetime, and the ratio of number of tester cases after control to those before control are investigated
机译：水痘带状疱疹病毒（VZV）是水痘和带状疱疹的传染病的原因，水痘和带状疱疹通常被称为水痘和带状疱疹。美国食品和药物管理局最近批准了一种VZV疫苗，用于儿童预防水痘。 VZV疫苗在日本，韩国和美国进行了测试，这些广泛的实验研究导致在美国获得最终批准。本文提出了一种水痘和带状疱疹的年龄相关模型。使用美国的统计数据，可以估算模型的参数值并计算数值解。研究了旨在减少易患水痘和带状疱疹的个体数量的各种控制策略的效果。特别是，研究了疫苗接种对平均感染年龄，人均一生中平均感染次数以及对照后与对照前的测试者病例数之比的影响。

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