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Computerized assessment of syntactic complexity in Alzheimer’s disease: a case study of Iris Murdoch’s writing

机译:阿尔茨海默氏病句法复杂性的计算机化评估:艾里斯·默多克(Iris Murdoch)的写作案例

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摘要

Currently, the majority of investigations of linguistic manifestations of neurodegenerative disorders such as Alzheimer’s disease are conducted based on manual linguistic analysis. Grammatical complexity is one of the language use characteristics sensitive to the effects of Alzheimer’s disease and is difficult to operationalize and measure using manual approaches. In the current study, we demonstrate the application of computational linguistic methods to automate the analysis of grammatical complexity. We implemented the Computerized Linguistic Analysis System (CLAS) based on the Stanford syntactic parser (Klein and Manning, Pattern Recognition, 38(9), 1407–1419, 2005) for longitudinal analysis of changes in syntactic complexity in language affected by neurodegenerative disorders. We manually validated CLAS scoring and used it to analyze writings of Iris Murdoch, a renowned Irish author diagnosed with Alzheimer’s disease. We found clear patterns of decline in grammatical complexity consistent with previous analyses of Murdoch’s writing conducted by Garrard, Maloney, Hodges, and Patterson (Brain, 128(250–260, 2005). CLAS is a fully automated system that may be used to derive objective and reproducible measures of syntactic complexity in language production and can be particularly useful in longitudinal studies with large volumes of language samples.
机译:目前,大多数关于神经退行性疾病(例如阿尔茨海默氏病)的语言表现的研究都是基于人工语言分析进行的。语法复杂性是对阿尔茨海默氏病的影响敏感的语言使用特征之一,并且难以使用手动方法进行操作和测量。在当前的研究中,我们演示了计算语言方法在自动化语法复杂性分析中的应用。我们基于斯坦福句法解析器(Klein and Manning,Pattern Recognition,38(9),1407–1419,2005)实施了计算机语言分析系统(CLAS),以纵向分析受神经变性疾病影响的语言的句法复杂性变化。我们手动验证了CLAS评分,并用它来分析Iris Murdoch的著作,Iris Murdoch是被诊断患有阿尔茨海默氏病的爱尔兰著名作家。我们发现语法复杂性下降的明显模式与Garrard,Maloney,Hodges和Patterson(Brain,128(250-260,2005))对默多克著作的先前分析相一致。CLAS是一种完全自动化的系统,可用于得出语言生产中语法复杂性的客观且可重现的度量,在大量语言样本的纵向研究中尤其有用。

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