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Large-scale ensemble averaging of ambulatory impedance cardiograms

机译:动态阻抗心电图的大规模总体平均

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Impedance cardiography has been used increasingly to measure human physiological responses to emotional and mentally engaging stimuli. The validity of large-scale ensemble averaging of ambulatory impedance cardiograms was evaluated for preejection period (PEP), interbeat interval, and dZ/dt_((min)) amplitude. We tested whether the average of "classical" 60-sec ensemble averages across periods with fixed activity, posture, physical load, social situation, and location could be accurately estimated from a single large-scale ensemble average spanning these entire periods. Impedance and electrocardiograms were recorded for about 24-h from 21 subjects. Recordings were scored by seven raters, using both methods for each subject. Good agreement (average intraclass correlation coefficient was .91) between both ensemble averaging methods was found for all three cardiac function measures. The results indicate that for unambiguous ambulatory impedance cardiograms, large-scale ensemble averaging is valid, which makes measuring prolonged changes in cardiac sympathetic activity by measuring ambulatory PEP feasible even in large epidemiological samples.
机译:阻抗心动图已越来越多地用于测量人类对情绪和精神参与刺激的生理反应。评估了动态阻抗心电图的大规模总体平均的有效性,以评估射血前期(PEP),心跳间隔和dZ / dt _((min))振幅。我们测试了是否可以通过跨整个周期的单个大型整体平均准确地估算出具有固定活动,姿势,身体负荷,社会状况和位置的各个时期的“经典” 60秒整体平均。记录了来自21位受试者的大约24小时的阻抗和心电图。记录由七个评分者对每个主题使用两种方法评分。在这三种心功能测量中,两种集成平均方法之间均具有良好的一致性(类内平均相关系数为0.91)。结果表明,对于明确的门诊阻抗心电图,大规模总体平均是有效的,这使得即使在大型流行病学样本中,通过测量门诊PEP来测量心脏交感神经活动的长期变化也是可行的。

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