Problems with the imprinting hypothesis of schizophrenia and autism

Matthew C. Keller

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Problems with the imprinting hypothesis of schizophrenia and autism

机译：精神分裂症和自闭症的烙印假设存在问题

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Crespi & Badcock (C&B) convincingly argue that autism and schizophrenia are diametric malfunctions of the social brain, but their core imprinting hypothesis is less persuasive. Much of the evidence they cite is unrelated to their hypothesis, is selective, or is overstated; their hypothesis lacks a clearly explained mechanism; and it is unclear how their explanation fits in with known aspects of the disorders.

机译：Crespi＆Badcock（C＆B）令人信服地认为，自闭症和精神分裂症是社交大脑的直径失调，但其核心烙印假设却缺乏说服力。他们引用的许多证据与他们的假设无关，具有选择性或被夸大了。他们的假设缺乏明确解释的机制；目前尚不清楚他们的解释如何与疾病的已知方面相吻合。

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《Behavioral and Brain Sciences》 |2008年第3期|p.273-274|共2页
作者
Matthew C. Keller;
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Department of Psychology and Institute for Behavioral Genetics, University of Colorado at Boulder, Boulder, CO 80309;

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正文语种 eng
中图分类心理学;
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机译：精神分裂症和自闭症的反差：低超意向性假说的神经证据
2. Imprint switch mutations at Rasgrf1 support conflict hypothesis of imprinting and define a growth control mechanism upstream of IGF1 [J] . Nadia M. Drake, Yoon Jung Park, Aditya S. Shirali, Mammalian Genome . 2009,第9a10期

机译：Rasgrf1的印记开关突变支持印记的冲突假设并定义了IGF1上游的生长控制机制
3. Imprint switch mutations at Rasgrf1 support conflict hypothesis of imprinting and define a growth control mechanism upstream of IGF1 [J] . Drake Nadia M., Park Yoon Jung, Shirali Aditya S., Mammalian genome: official journal of the International Mammalian Genome Society . 2009,第9a10期

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4. The dopamine hypothesis of schizophrenia: an updated perspective [C] . Kenneth S. Kendler Philosophical Issues in Psychiatry :the Nature and Sources of Historical Change. . 2015

机译：精神分裂症的多巴胺假说：更新的视角
5. Imprinting in the schizophrenia-associated gene GABRB2 encoding GABAA receptor beta2 subunit. [D] . Pun, Wing Frank. 2010

机译：印在精神分裂症相关基因GABRB2编码GABAA受体beta2亚基。
6. Schizophrenia and Autism as Contrasting Minds: Neural Evidence for the Hypo-Hyper-Intentionality Hypothesis [O] . Angela Ciaramidaro, Sven Bölte, Sabine Schlitt, 2015

机译：精神分裂症和自闭症的反差：低超意向性假说的神经证据
7. Schizophrenia and Autism as Contrasting Minds: Neural Evidence for the Hypo-Hyper-Intentionality Hypothesis [O] . Ciaramidaro, Angela, Bölte, Sven, Schlitt, Sabine, 2017

机译：精神分裂症和自闭症的反差：低超意向性假说的神经证据
8. Schizophrenia Bulletin, Volume 27, No. 3, 2001. Issue Theme: The DevelopmentalEtiology of Schizophrenia Hypothesis: What is the Evidence [R] . Hsiao, J. K. 2001

机译：精神分裂症公报，第27卷，第3期，2001年。问题主题：精神分裂症假说的发展病因：证据是什么

Problems with the imprinting hypothesis of schizophrenia and autism

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