Buffers May Adversely Affect Model Lipid Membranes: A Cautionary Tale

Teresa Peiru0001 o-Salvador Oscar Ces Richard H. Templer and Annela M. Seddon

首页> 外文期刊>Biochemistry >Buffers May Adversely Affect Model Lipid Membranes: A Cautionary Tale

【24h】

Buffers May Adversely Affect Model Lipid Membranes: A Cautionary Tale

机译：缓冲液可能会对模型脂质膜产生不利影响：一个警告性的故事

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The effects of biological buffers on lipids have notnbeen fully investigated because of the long-standing assump-ntion that these buffers are too hydrophilic to substantiallyninteract with the lipid membrane. We present evidence thatnfor some buffers, this is not necessarily the case. Our researchnpoints toward a membrane softening effect caused by thenbuffermolecules interacting with the headgroup region of thenlipid. Changes in the elastic properties of the membrane arenknown to control membrane protein behavior; this worknserves as a warning for the design of assays utilizing modelnmembranes in the presence of buffers.

机译：由于长期以来一直认为这些缓冲液亲水性太强而无法与脂质膜充分相互作用，因此尚未对生物缓冲液对脂质的作用进行充分研究。我们提供的证据表明，对于某些缓冲区，情况并非一定如此。我们的研究指向由缓冲分子与脂类的头基区域相互作用引起的膜软化作用。膜的弹性特性的变化可控制膜蛋白的行为，这是众所周知的。这项工作为在存在缓冲液的情况下利用模型膜进行分析的设计提供了警告。

著录项

来源
《Biochemistry》 |2009年第47期|p.11149-11151|共3页
作者
Teresa Peiru0001 o-Salvador Oscar Ces Richard H. Templer and Annela M. Seddon;
展开▼
作者单位

‡Department of Chemistry, Imperial College London, Exhibition Road, London SW7 2AZ, U.K., and §Chemical Biology Centre,Imperial College London, Exhibition Road, London SW7 2AZ, U.K.;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. Buffers Affect the Bending Rigidity of Model Lipid Membranes [J] . He?le?ne Bouvrais, Lars Duelund, John H. Ipsen Langmuir: The ACS Journal of Surfaces and Colloids . 2014,第1期

机译：缓冲液影响模型脂质膜的抗弯刚度
2. How Anionic Lipids Affect Spatiotemporal Properties of KRAS4B on Model Membranes [J] . Ngo Van A., Sarkar Sumantra, Neale Chris, The journal of physical chemistry, B. Condensed matter, materials, surfaces, interfaces & biophysical . 2020,第26期

机译：阴离子脂质如何影响模型膜上KRAS4B的时空性质
3. Galactoglycerolipid Lipase PGD1 Is Involved in Thylakoid Membrane Remodeling in Response to Adverse Environmental Conditions in Chlamydomonas [J] . Du Zhi-Yan, Lucker Ben F., Zienkiewicz Krzysztof, The Plant Cell . 2018,第2期

机译：吡酰甘油胆胆脂脂肪酶PGD1响应衣原体中的不利环境条件，参与囊体膜重塑
4. ALTERED FORMATIONS OF SPECIAL EUBACTERIAL MEMBRANE LIPIDS AFFECT BACTERIAL INTERACTIONS WITH EUKARYOTIC HOSTS [C] . O. Geiger, I. M. Lopez-Lara, C. Sohlenkamp International Conference of the African Association for Biological Nitrogen Fixation . 2008

机译：特殊的细菌膜脂质的改变形成与真核宿主的细菌相互作用
5. The Role of Urbanization in African Human Development: A Cautionary Tale: The Case of Ethiopia [D] . ?Oranga, Beryl Adongo 2020

机译：城市化在非洲人类发展中的作用：一种警示故事：埃塞俄比亚的案例
6. Galactoglycerolipid Lipase PGD1 Is Involved in Thylakoid Membrane Remodeling in Response to Adverse Environmental Conditions in Chlamydomonas [O] . Zhi-Yan Du, Ben F. Lucker, Krzysztof Zienkiewicz, 2018

机译：半乳甘油脂酶PGD1参与类囊体膜重塑响应衣藻的不利环境条件。
7. Galactoglycerolipid Lipase PGD1 Is Involved in Thylakoid Membrane Remodeling in Response to Adverse Environmental Conditions in Chlamydomonas [O] . Zhi-Yan Du, Ben Franklin Lucker, KRZYSZTOF ZIENKIEWICZ, 2018

机译：吡酰甘油糖脂脂酶PGD1响应衣原体中的不利环境条件参与囊体膜重塑
8. Mathematical Modeling of Transport of Lipid-Soluble Ions and Ion-Carrier Complexes Through Lipid Bilayer Membranes. [R] . Levie, R. 1978

机译：脂质双层膜运输脂溶性离子和离子载体复合物的数学模型。

Buffers May Adversely Affect Model Lipid Membranes: A Cautionary Tale

摘要

著录项

相似文献

相关主题

期刊订阅