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DELIMINATE—a fast and efficient method for loss-less compression of genomic sequences

机译:定义—一种快速有效的基因组序列无损压缩方法

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Summary: An unprecedented quantity of genome sequence data is currently being generated using next-generation sequencing platforms. This has necessitated the development of novel bioinformatics approaches and algorithms that not only facilitate a meaningful analysis of these data but also aid in efficient compression, storage, retrieval and transmission of huge volumes of the generated data. We present a novel compression algorithm (DELIMINATE) that can rapidly compress genomic sequence data in a loss-less fashion. Validation results indicate relatively higher compression efficiency of DELIMINATE when compared with popular general purpose compression algorithms, namely, gzip, bzip2 and lzma.
机译:简介:当前正在使用下一代测序平台生成数量空前的基因组序列数据。这就需要开发新颖的生物信息学方法和算法,这些方法和算法不仅有助于对这些数据进行有意义的分析,而且有助于有效地压缩,存储,检索和传输大量生成的数据。我们提出了一种新颖的压缩算法(DELIMINATE),该算法可以以无损方式快速压缩基因组序列数据。验证结果表明,与流行的通用压缩算法gzip,bzip2和lzma相比,DELIMATE的压缩效率相对较高。

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