Proteasomes and Transplantology: Current State of the Problem and the Search for Promising Trends

Karpova Ya. D.; Bozhok G. A.; Alabedalkarim N. M.; Lyupina Yu. V.; Astakhova T. M.; Legach E. I.; Sharova N. P.

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Proteasomes and Transplantology: Current State of the Problem and the Search for Promising Trends

机译：蛋白酶体和移植术：问题的现状和有希望的趋势的搜索

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Basic research of the structure and functions of multiple forms of proteasomes is overviewed. The proteasomes of liver, acting as a primary lymphoid organ in embryogenesis, displaying nonspecific local immunity, and providing development of tolerance to food and other foreign antigens during the lifespan, are described. The role of individual forms of liver proteasomes in transplantology is considered as well as their utility as markers for endocrine transplant survival.

机译：概述了多种形式的蛋白酶体的结构和功能的基础研究。描述了肝脏的蛋白酶体，其在胚胎发生中起主要的淋巴器官的作用，显示出非特异性的局部免疫力，并在寿命期间提供了对食物和其他外来抗原的耐受性。肝蛋白酶体的各种形式在移植术中的作用以及它们作为内分泌移植存活标志物的效用均被考虑。

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《Biology Bulletin》 |2017年第3期|237-244|共8页
作者
Karpova Ya. D.; Bozhok G. A.; Alabedalkarim N. M.; Lyupina Yu. V.; Astakhova T. M.; Legach E. I.; Sharova N. P.;
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Russian Acad Sci, Koltsov Inst Dev Biol, Ul Vavilova 26, Moscow 119334, Russia;

Natl Acad Sci Ukraine, Inst Problems Cryobiol & Cryomed, Ul Pereyaslavskaya 23, UA-61016 Kharkov, Ukraine;

Natl Acad Sci Ukraine, Inst Problems Cryobiol & Cryomed, Ul Pereyaslavskaya 23, UA-61016 Kharkov, Ukraine;

Russian Acad Sci, Koltsov Inst Dev Biol, Ul Vavilova 26, Moscow 119334, Russia;

Russian Acad Sci, Koltsov Inst Dev Biol, Ul Vavilova 26, Moscow 119334, Russia;

Natl Acad Sci Ukraine, Inst Problems Cryobiol & Cryomed, Ul Pereyaslavskaya 23, UA-61016 Kharkov, Ukraine;

Russian Acad Sci, Koltsov Inst Dev Biol, Ul Vavilova 26, Moscow 119334, Russia;

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Proteasomes and Transplantology: Current State of the Problem and the Search for Promising Trends

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