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Ethanol as a Possible Modifier of Acute Radiation Lesions of the Brain

机译:乙醇作为脑急性辐射病变的可能改性剂

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Cerebral effects were studied in experiments on rats exposed to acute gamma-radiation of the head at cerebral doses, with previous or subsequent administration of different ethanol doses. Both factors cause similar changes in neurological symptoms and neuromorphological effects. Ethanol before irradiation did not significantly modify the state of neurons, but caused the appearance of synapses degenerating via filament type. After irradiation, ethanol at the threshold dose did not change and at a large tranquilizing dose slightly increased radiation changes in neurons and synapses. The effects of radio-modification depended on the dose of ethanol and the time of its administration.
机译:在暴露于脑剂量的急性γ-辐射的大鼠的实验中研究了脑效应,以前或随后给予不同的乙醇剂量。两种因素导致神经系统症状和神经形态效应的相似变化。辐照前的乙醇没有显着修饰神经元的状态,而是导致通过细丝型退化的突触的外观。在照射后,阈值剂量的乙醇没有改变,并且在大的静脉化剂量下略微增加神经元和突触的辐射变化。无线电改性的影响依赖于乙醇剂量和给药时间。

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