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首页> 外文期刊>Biomedical Engineering, IEEE Transactions on >Characterization of a 50-$Omega$ Exposure Setup for High-Voltage Nanosecond Pulsed Electric Field Bioexperiments
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Characterization of a 50-$Omega$ Exposure Setup for High-Voltage Nanosecond Pulsed Electric Field Bioexperiments

机译：高压纳秒脉冲电场生物实验的50-Omega $曝光设置的特性

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摘要

An exposure system for a nanosecond pulsed electric field is presented and completely characterized in this paper. It is composed of a high-voltage generator and an applicator: the biological cuvette. The applied pulses have high intensities (up to 5 kV), short durations (3 and 10 ns), and different shapes (square, bipolar). A frequency characterization of the cuvette is carried out based on both an analytical model and experimental measurements ( S$_{11}$) in order to determine its matching bandwidth. High voltage measurements in the time domain are performed. Results show that the cuvette is well adapted to 10-ns pulses and limited to those of 3 ns. The rise/fall times of the pulses should not be less than 1.5 ns. In addition, numerical calculation providing voltage distribution within the cuvette is performed using an in-house finite-difference time-domain code. A good level of voltage homogeneity across the cuvette electrodes is obtained, as well as consistency with experimental data for all the applied pulses.
机译：提出了一种纳秒脉冲电场的曝光系统，并对其进行了完整的表征。它由高压发生器和施药器组成：生物比色皿。所施加的脉冲具有高强度（最高5 kV），持续时间短（3 ns和10 ns）以及不同的形状（正方形，双极性）。基于分析模型和实验测量值（S $ _ {11} $）对比色杯进行频率表征，以确定其匹配带宽。在时域中执行高压测量。结果表明，比色杯非常适合10 ns的脉冲，并且限于3 ns的脉冲。脉冲的上升/下降时间不应少于1.5 ns。此外，使用内部有限差分时域代码执行提供比色杯内电压分布的数值计算。在比色皿电极上获得了良好的电压均匀性，并且与所有施加脉冲的实验数据保持一致。

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