Synthesis of fluorescent molecular probes specific for the receptor of blepharismone, a mating-inducing pheromone of the ciliate Blepharisma japonicum

Yoshiyuki Uruma; Mayumi Sugiura; Terue Harumoto; Yoshinosuke Usuki; Hideo Iio

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Synthesis of fluorescent molecular probes specific for the receptor of blepharismone, a mating-inducing pheromone of the ciliate Blepharisma japonicum

机译：荧光素的受体的特异性荧光分子探针的合成，该化合物是纤毛虫的交配诱导信息素。

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Blepharismone (gamone 2) is a mating-inducing pheromone of the ciliate Blepharisma japonicum. N-Pyrenylbutyryl-blepharismone and N-biphenylacetyl-blepharismone, which are fluorescent derivatives of blepharismone, were synthesized as molecular probes for the gamone 2 receptor. Further, we proved that they have inhibitory activities against the blepharismone-induced monotypic pairing of B. japonicum.

机译：头孢苯醚酮（gamone 2）是纤毛虫（Blepharisma japonicum）的交配诱导信息素。合成了作为邻苯二甲酮的荧光探针的N-吡啶基丁苯基-邻苯二甲酮和N-联苯乙酰基-邻苯二甲酮作为gamone 2受体的分子探针。进一步，我们证明了它们对日本豆根瘤菌菌素诱导的单型配对具有抑制活性。

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来源
《Bioorganic and Medicinal Chemistry》 |2007年第4期|1622-1627|共6页
作者
Yoshiyuki Uruma; Mayumi Sugiura; Terue Harumoto; Yoshinosuke Usuki; Hideo Iio;
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作者单位

Department of Material Science, Graduate School of Science, Osaka City University, Osaka 558-8585, Japan;

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原文格式 PDF
正文语种 eng
中图分类药学;生物化学;
关键词
fluorescent probes; cell-cell interaction; ciliate phero-mones; inhibitory activity;

机译：荧光探针细胞间相互作用纤毛信息素;抑制活性;

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1. Synthesis of fluorescent molecular probes specific for the receptor of blepharismone, a mating-inducing pheromone of the ciliate Blepharisma japonicum. [J] . Uruma Y, Sugiura M, Harumoto T, Bioorganic and medicinal chemistry . 2007,第4期

机译：特异于日本毛纤虫的交配诱导信息素，brophrisismone受体的荧光分子探针的合成。
2. Synthesis of fluorescent molecular probes specific for the receptor of blepharismone, a mating-inducing pheromone of the ciliate Blepharisma japonicum. [J] . UrumaY, SugiuraM, HarumotoT, Bioorganic and Medicinal Chemistry . 2007,第4期

机译：特异于日本毛纤毛虫交配诱导的信息素，blepharismone受体的荧光分子探针的合成。
3. Practical synthesis of blepharismone, a mating inducing pheromone of Blepharisma japonicum [J] . Takihiro H, Uruma Y, Usuki Y, Tetrahedron, Asymmetry: The International Journal for Repid Publication on all Aspects of Asymmetry in Orgainc, Inorganic, Organometallic, Physical and Bio-Organic Chemistry . 2006,第16期

机译：实用的日本血吸虫交配诱导信息素blepharismone的合成
4. Synthesis,bioactivity and receptor binding of fluorescent NBD labeled analogs of the tridecapeptide mating pheromone of saccharomyces cerevisiae [C] . Fa-Xiang Ding, B.K.Lee, Jeffrey M.Becker, the International Peptide Symposium . 2001

机译：荧光NBD的合成，生物活性和受体结合标记的酿酒酵母交配信息素的标记类似物
5. Molecular recognition in water: Design, synthesis, and characterization of rigid molecular receptors and enzymatic mechanistic probes. [D] . Hoppe, Robert William. 2016

机译：水中的分子识别：刚性分子受体和酶促机理探针的设计，合成和表征。
6. Identification characterization and complete amino acid sequence of the conjugation-inducing glycoprotein (blepharmone) in the ciliate Blepharisma japonicum [O] . Mayumi Sugiura, Terue Harumoto 2001

机译：鉴定表征和完整氨基酸结合诱导糖蛋白（blepharmone）的序列纤毛日本血吸虫
7. Synthesis of Blepharismone, a Conjugation Inducing Gamone in Ciliate Blepharisma [O] . Takashi TOKOROYAMA, Shinichi HORII, Takashi KUBOTA 1973

机译：Blpharismone的合成，Ciiliant Blepharisma的缀合物诱导的沙发桥

Synthesis of fluorescent molecular probes specific for the receptor of blepharismone, a mating-inducing pheromone of the ciliate Blepharisma japonicum

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