Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase

Chee Yan Choo; Yusuke Hirasawa; Chiaki Karimata; Koichiro Koyama; Mitsuhiro Sekiguchi; Junichi Kobayashi; Hiroshi Morita

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Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase

机译：Carinatumins A-C，Carinatum石蒜的新生物碱抑制乙酰胆碱酯酶

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Three new Lycopodium alkaloids, carinatumins A-C (1-3), have been isolated from the club moss Lycopodium carinatum. Structures and stereochemistry of 1-3 were elucidated on the basis of 2D NMR correlations. Carinatumins A (1) and B (2) exhibited a potent inhibitory activity against acetylcholinesterase.

机译：从俱乐部苔藓Carinatum上分离出了三种新的Lycopodium生物碱，carinatumins A-C（1-3）。根据2D NMR相关性阐明了1-3的结构和立体化学。 Carinatumins A（1）和B（2）对乙酰胆碱酯酶表现出有效的抑制活性。

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来源
《Bioorganic and Medicinal Chemistry》 |2007年第4期|1703-1707|共5页
作者
Chee Yan Choo; Yusuke Hirasawa; Chiaki Karimata; Koichiro Koyama; Mitsuhiro Sekiguchi; Junichi Kobayashi; Hiroshi Morita;
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作者单位

Faculty of Pharmaceutical Sciences, Hoshi University, Shinagawa-ku, Tokyo 142-8501, Japan;

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原文格式 PDF
正文语种 eng
中图分类药学;生物化学;
关键词
alkaloids; lycopodium; carinatumin A; carinatumin B; carinatumin C; acetylcholinesterase;

机译：生物碱番茄Carinatumin A;Carinatumin B;Carinatumin C;乙酰胆碱酯酶;

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1. Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase. [J] . Choo CY, Hirasawa Y, Karimata C, Bioorganic and medicinal chemistry . 2007,第4期

机译：Carinatumins A-C，carinatum石蒜的新生物碱抑制乙酰胆碱酯酶。
2. Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase. [J] . ChooCY, HirasawaY, KarimataC, Bioorganic and Medicinal Chemistry . 2007,第4期

机译：Carinatumins A-C，Carinatum石蒜的新生物碱抑制乙酰胆碱酯酶。
3. Lycoparins A-C, new alkaloids from Lycopodium casuarinoides inhibiting acetylcholinesterase. [J] . Hirasawa Y, Kato E, Kobayashi J, Bioorganic and medicinal chemistry . 2008,第11期

机译：Lycoparins A-C，来自casuarinoides的Lycopodium casuarinoides的新生物碱，可抑制乙酰胆碱酯酶。
4. Comparison Accuracy of Multi-Layer Perceptron and DNN in QSAR Classification for Acetylcholinesterase Inhibitors [C] . Mushliha, Alhadi Bustamam, Arry Yanuar, International Conference on Artificial Intelligence and Mechatronics Systems . 2021

机译：乙酰胆碱酯酶抑制剂QSAR分类中多层Perceptron和DNN的比较精度
5. Part I - Synthesis of the tetracyclic skeleton of the Lycopodium alkaloid lycopladine H Part II - Synthesis of the tetracyclic core of the apparicine class of indole alkaloids via a key intermolecular nitrosoalkene conjugate addition. [D] . Chauhan, Pradeep S. 2015

机译：第一部分-通过关键的分子间亚硝基链烯共轭物的添加，合成淫羊Ly生物碱番茄红素H的四环骨架。第二部分-合成吲哚生物碱类装置的四环核。
6. Wild Argentinian Amaryllidaceae a New Renewable Source of the Acetylcholinesterase Inhibitor Galanthamine and Other Alkaloids [O] . Javier E. Ortiz, Strahil Berkov, Natalia B. Pigni, 2012

机译：阿根廷野生金枪鱼科乙酰胆碱酯酶抑制剂加兰他敏和其他生物碱的新可再生来源
7. Hupercumines A and B, Lycopodium Alkaloids from Huperzia cunninghamioides, Inhibiting Acetylcholinesterase [O] . -1

机译：Hupercumines A和B，来自Huperzia Cunninghamioides的氯氰酸生物碱，抑制乙酰胆碱酯酶

Carinatumins A-C, new alkaloids from Lycopodium carinatum inhibiting acetylcholinesterase

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