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首页> 外文期刊>Bioprocess and Biosystems Engineering >Computational fluid dynamics (CFD) analysis of airlift bioreactor: effect of draft tube configurations on hydrodynamics, cell suspension, and shear rate
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Computational fluid dynamics (CFD) analysis of airlift bioreactor: effect of draft tube configurations on hydrodynamics, cell suspension, and shear rate

机译：气举生物反应器的计算流体动力学（CFD）分析：引流管配置对流体动力学，细胞悬浮液和剪切速率的影响

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摘要

The biomass productivity of microalgae cells mainly depends on the hydrodynamics of airlift bioreactor (ABR). Thus, the hydrodynamics of concentric tube ABR was initially studied using two-phase three-dimensional CFD simulations with the Eulerian-Lagrangian approach. The performance of ABR (17 L) was examined for different configurations of the draft tube using various drag models such as Grace, Ishii-Zuber, and Schiller-Naumann. The gas holdups in the riser and the downcomer were well predicted using E-L approach. This work was further extended to study the dispersion of microalgae cells in the ABR using three-phase CFD simulations. In this model (combined E-E and E-L), the solid phase (microalgae cells) was dispersed into the continuous liquid phase (water), while the gas phase (air bubbles) was modeled as a particle transport fluid. The effect of non-drag forces such as virtual mass and lift forces was also considered. Flow regimes were explained on the basis of the relative gas holdup distribution in the riser and the downcomer. The microalgae cells were found in suspension for the superficial gas velocities of 0.02-0.04 m s(-1) experiencing an average shear of 23.52-44.56 s(-1) which is far below the critical limit of cell damage.
机译：微藻细胞的生物量生产力主要取决于空运生物反应器（ABR）的流体动力学。因此，最初使用欧拉-拉格朗日方法进行的两相三维CFD模拟研究了同心管ABR的流体动力学。使用各种阻力模型（例如Grace，Ishii-Zuber和Schiller-Naumann），针对引流管的不同配置检查了ABR（17 L）的性能。使用E-L方法可以很好地预测上升管和下降管中的气体滞留量。这项工作进一步扩展为使用三相CFD模拟研究微藻细胞在ABR中的分散。在此模型（E-E和E-L组合）中，固相（微藻细胞）分散在连续的液相（水）中，而气相（气泡）被建模为颗粒传输流体。还考虑了非拖动力（例如虚拟质量和提升力）的影响。根据上升管和下降管中的相对含气量分布来解释流态。在悬浮液中发现微藻细胞的表面气体速度为0.02-0.04 m s（-1），平均剪切力为23.52-44.56 s（-1），远低于细胞损伤的临界极限。

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