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Performance evaluation of acetone-butanol continuous flash extractive fermentation process

机译：丙酮-丁醇连续闪蒸发酵工艺性能评价

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摘要

A general mathematical model for performance evaluation of acetone-butanol continuous flash extractive fermentation system was formulated in the terms of productivity, energy requirement (energy utilization efficiency) and product purity. The simulation results based on experimental data showed that the most pronounced performance improvement could be achieved by using highly concentrated substrate as feed and the increase in solvent dilution rate could only improve the total productivity at the expense of energy utilization efficiency. A two-vessel partial flash system, with the first vessel of two to three plates and the second vessel as a complete flash vessel, is required to ensure high product purity. This method of mathematical formulation and analysis could be used and extended as a general tool to other bioprocesses equipped with multiple in situ recovery systems.
机译：从生产率，能源需求（能源利用效率）和产品纯度的角度出发，建立了丙酮-丁醇连续闪蒸发酵系统性能评价的通用数学模型。基于实验数据的模拟结果表明，使用高度浓缩的底物作为进料可以实现最显着的性能改善，而溶剂稀释率的提高只能提高总生产率，却以能源利用效率为代价。为了确保高产品纯度，需要一个两容器的部分闪蒸系统，第一个容器为两到三个板，第二个容器为一个完整的闪蒸容器。这种数学公式化和分析方法可以用作通用工具，并扩展到其他配备多个原位回收系统的生物过程。

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