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Special issue on bioprocess modelling and control

机译:生物过程建模与控制特刊

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摘要

Nowadays, bioprocess modelling, dynamic analysis, optimisation, monitoring and control play an ever-increasing role in various fields, ranging from the production of high-added-value pharmaceuticals to environmental issues such as wastewater treatment. Besides the development of methods and tools for the identification of unknown model parameters, the on-line reconstruction of non-measured variables (using state estimation techniques or "software sensors"), and the real-time optimisation and control of bioprocesses, bioprocess engineering also encompasses new challenges in dynamic metabolic analysis, the deduction of reduced-order, simplified, models, and the study of cell regulation mechanisms. This special journal issue of Bioprocess and Biosystems Engineering includes eight articles reporting on recent research developments in these various areas.
机译:如今,生物过程建模,动态分析,优化,监视和控制在从高附加值药品的生产到废水处理等环境问题的各个领域中发挥着越来越重要的作用。除了开发用于识别未知模型参数的方法和工具之外,还可以在线重构未测量的变量(使用状态估计技术或“软件传感器”),以及对生物过程,生物过程工程进行实时优化和控制还包括动态代谢分析中的新挑战,降阶,简化模型的推论以及细胞调控机制的研究。这本《生物过程和生物系统工程》的特殊期刊包括八篇文章,报道了这些领域的最新研究进展。

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