Enhanced production of avermectin B1a by medium optimization and glucose feeding with Streptomyces avermilitis

Xu Zhinan; Cen Peilin

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Enhanced production of avermectin B1a by medium optimization and glucose feeding with Streptomyces avermilitis

机译：通过培养基优化和葡萄糖饲喂链霉菌阿维链炎提高阿维菌素B1a的产量

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Avermectin B1a is an important macrolide an- tibiotic with potent anthlemintic and insecticidal activity. The objective of this study was to enhance productivity of Avermectin B1a by optimizing culture medium and glucose Feeding fermentation. Results showed that B1A concen- Tration was increased by 48.6/100 through optimization of Nitrogen, carbon sources as well as supplement of 0.2 mM Co~2+.

机译：阿维菌素B1a是一种重要的大环内酯类抗生素，具有强大的驱虫和杀虫活性。这项研究的目的是通过优化培养基和葡萄糖进料发酵来提高阿维菌素B1a的生产率。结果表明，通过优化氮，碳源以及补充0.2 mM Co〜2 +，B1A浓度提高了48.6 / 100。

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《Bioprocess Engineering》 |1999年第1期|p.67-71|共5页
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Xu Zhinan; Cen Peilin;
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正文语种 eng
中图分类生物工程学（生物技术）;
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专利

1. Enhanced production of avermectin Bla by medium optimization and glucose feeding with Streptomyces avermilitis [J] . Xu Zhinan, Cen Peilin Bioprocess Engineering: Bioreactors Upstream and Downstream Processes Measurement and Control . 1999,第1期

机译：通过培养基优化和葡萄糖饲喂链霉菌平均乳腺炎提高阿维菌素Bla的产量
2. Stimulation of avermectin B1a biosynthesis in Streptomyces avermilitis by feeding glucose and propionate [J] . Xu Zhinan, Cen Peilin* Biotechnology Letters . 1999,第1期

机译：喂葡萄糖和丙酸酯刺激链霉菌性阿维链霉菌中阿维菌素B1a的生物合成
3. Medium optimization for the production of avermectin B1a by Streptomyces avermitilis 14-12A using response surface methodology [J] . Gao H, Liu M, Liu JT, Bioresource Technology: Biomass, Bioenergy, Biowastes, Conversion Technologies, Biotransformations, Production Technologies . 2009,第17期

机译：使用响应面法优化阿维链霉菌14-12A生产阿维菌素B1a的培养基
4. Enhancement of ε-Poly-l-lysine Production by Streptomyces Diastatochromogenes T17 Using Acidic Adaptive Evolution and Medium Optimization [C] . Fei Mi, Chao Yu, Xidong Ren, International Symposium on the Frontiers of Biotechnology and Bioengineering . 2019

机译：使用酸性自适应演化和中式优化来增强ε-聚-L-赖氨酸生产T17的ε-聚-L-赖氨酸生产
5. Effect of feed delivery time and concentrate level on rhythms of plasma metabolite, enzyme, and hormone levels, glucose tolerance and milk production in dairy cows [D] . Furedi, Carole J. M. 2007

机译：饲料输送时间和浓缩液水平对奶牛血浆代谢产物节律，酶和激素水平，葡萄糖耐量和产奶量的影响
6. Optimization of Fermentation Medium for the Production of Glucose Isomerase Using Streptomyces sp. SB-P1 [O] . Sheetal Bhasin, H. A. Modi 2005

机译：利用链霉菌优化发酵培养基生产葡萄糖异构酶。 SB-P1
7. Medium optimization for the production of avermectin B1a by Streptomyces avermitilis 14-12A using response surface methodology [O] . Gao H, Liu M, Liu JT, 2009

机译：medium optimization for the production of avermectin B1a by streptomyces avermitilis 14-12a using response surface methodology

Enhanced production of avermectin B1a by medium optimization and glucose feeding with Streptomyces avermilitis

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