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首页> 外文期刊>Brain and cognition >Event-related potentials in adolescents with combined ADHD and CD disorder: A single stimulus paradigm
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Event-related potentials in adolescents with combined ADHD and CD disorder: A single stimulus paradigm

机译：合并多动症和CD障碍的青少年事件相关电位：单一刺激范式

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摘要

Some studies of the event-related potentials demonstrated a reduction of the voluntary component P3 (P300 or P3b) in youngsters with the attention deficit/hyperactivity disorder (ADHD) or in conduct disorders (CD), and a reduction of the automatic processing component, mismatch negativity, in patients with both ADHD and CD (ADHD + CD). Recently, a passive auditory P3 potential has been elicited by a single stimulus. We therefore tried this potential study in 20 healthy subjects and 20 teenagers with ADHD + CD to search for further evidence of the altered automatic cerebral processing in the latter. Subjects also answered a self-report Dimensional Assessment of Personality Pathology (DAPP). The patient group scored significantly higher on most DAPP traits that reflect problems of emotion control, showed significantly prolonged P2, N2, and P3, and reduced P3. In all subjects Stimulus Seeking was positively correlated with P3 latencies at Fz, Cz, and Pz, and with P3 amplitude at Cz. This study suggests that youngsters with ADHD + CD had pronounced emotion dysregulation, and prominent deficit in passive attention, as reflected by the automatic processing of auditory stimuli.
机译：对事件相关电位的一些研究表明，患有注意力缺陷/多动障碍（ADHD）或行为障碍（CD）的年轻人自愿成分P3（P300或P3b）减少，自动加工成分减少， ADHD和CD（ADHD + CD）患者的失配阴性。近来，通过单个刺激已引起被动听觉P3电位。因此，我们在20名健康受试者和20名患有ADHD + CD的青少年中尝试了这项潜在研究，以寻找后者中自动大脑加工改变的进一步证据。受试者还回答了自我报告的人格病理维度评估（DAPP）。在反映情绪控制问题，显示P2，N2和P3显着延长，P3降低的大多数DAPP特质上，患者组得分明显较高。在所有受试者中，刺激刺激与Fz，Cz和Pz处的P3潜伏期以及Cz处的P3振幅均呈正相关。这项研究表明，患有ADHD + CD的年轻人表现出明显的情绪失调，并且在被动注意力方面表现出明显的缺陷，这通过听觉刺激的自动处理得以体现。

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