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首页> 外文期刊>Breast Cancer Research and Treatment >Extremely low-frequency electromagnetic fields exposure and female breast cancer risk: a meta-analysis based on 24,338 cases and 60,628 controls
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Extremely low-frequency electromagnetic fields exposure and female breast cancer risk: a meta-analysis based on 24,338 cases and 60,628 controls

机译:极低频电磁场暴露和女性乳腺癌风险:基于24,338例病例和60,628例对照的荟萃分析

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摘要

Exposure to extremely low-frequency electromagnetic fields (ELF-EMF) has been suggested to increase female breast cancer risk; however, the data have been inconclusive. In order to derive a more precise estimation of the relationship, a meta-analysis was performed. Medline, PubMed, Embase, the Cochrane Library and Web of Science were searched. Crude ORs with 95% CIs were used to assess the strength of association between ELF-EMF exposure and female breast cancer risk. A total of 15 studies published over the period 2000 to 2009 including 24,338 cases and 60,628 controls were involved in this meta-analysis. The results showed no significant association between ELF-EMF exposure and female breast cancer risk in total analysis (OR = 0.988, 95% CI = 0.898–1.088) and in all the subgroup analyses by exposure modes, menopausal status, and estrogen receptor status. This result is in accordance with the previous meta-analysis carried out by Erren in 2000. In conclusion, this meta-analysis suggests that ELF-EMF exposure has no association with the susceptibility of female breast cancer.
机译:已建议暴露于极低频电磁场(ELF-EMF)会增加女性乳腺癌的风险;但是,数据尚无定论。为了获得对关系的更精确的估计,进行了荟萃分析。搜索Medline,PubMed,Embase,Cochrane图书馆和Web of Science。使用具有95%CI的原始OR评估ELF-EMF暴露与女性乳腺癌风险之间的关联强度。该荟萃分析涉及2000年至2009年期间发表的15项研究,包括24,338例病例和60,628例对照。结果显示,在总体分析中,ELF-EMF暴露与女性乳腺癌风险之间无显着关联(OR = 0.988,95%CI = 0.898–1.088),并且在所有亚组分析中,暴露方式,更年期状态和雌激素受体状态均无相关性。该结果与Erren先前在2000年进行的荟萃分析一致。最后,该荟萃分析表明ELF-EMF暴露与女性乳腺癌的易感性无关。

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