首页> 外文期刊>Breast Cancer Research and Treatment >Levels of circulating regulatory CD4+CD25+ T cells are decreased in breast cancer patients after vaccination with a HER2eu peptide (E75) and GM-CSF vaccine★
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Levels of circulating regulatory CD4+CD25+ T cells are decreased in breast cancer patients after vaccination with a HER2eu peptide (E75) and GM-CSF vaccine★

机译:接种HER2 / neu肽(E75)和GM-CSF疫苗的乳腺癌患者中循环调节性CD4 + CD25 + T细胞水平降低★

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摘要

We are conducting clinical trials in breast cancer (BrCa) patients to test the HER2eu peptide vaccine (E75). We have investigated the impact of this vaccine on circulating levels of regulatory T cells (Treg) and the resulting effects on antitumor responses.
机译:我们正在乳腺癌(BrCa)患者中进行临床试验,以测试HER2 / neu肽疫苗(E75)。我们已经研究了这种疫苗对循环调节性T细胞(Treg )的影响及其对抗肿瘤反应的影响。

著录项

  • 来源
    《Breast Cancer Research and Treatment》 |2006年第1期|17-29|共13页
  • 作者单位

    Clinical Breast Care Project Department of Surgery Walter Reed Army Medical Center;

    Clinical Breast Care Project Department of Surgery Walter Reed Army Medical CenterClinical Breast Care Project Immunology and Research Center Uniformed Services University of the Health Sciences;

    Clinical Breast Care Project Immunology and Research Center Uniformed Services University of the Health Sciences;

    Clinical Breast Care Project Immunology and Research Center Uniformed Services University of the Health Sciences;

    Clinical Breast Care Project Department of Surgery Walter Reed Army Medical Center;

    Clinical Breast Care Project Department of Surgery Walter Reed Army Medical CenterClinical Breast Care Project Immunology and Research Center Uniformed Services University of the Health Sciences;

    Clinical Breast Care Project Immunology and Research Center Uniformed Services University of the Health Sciences;

    Clinical Breast Care Project Department of Surgery Walter Reed Army Medical CenterClinical Breast Care Project Immunology and Research Center Uniformed Services University of the Health SciencesClinical Breast Care Project Immunology and Research Center Uniformed Services University of the Health Sciences;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    CD4+CD25+ T cells; E75; HER2eu; peptide vaccine; regulatory T cells;

    机译:CD4 + CD25 + T细胞;E75;HER2 / neu;肽疫苗;调节性T细胞;

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