Bilateral Breast Reconstruction and the Role of Prophylactic Mastectomy

Susan E. MacLennan

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Bilateral Breast Reconstruction and the Role of Prophylactic Mastectomy

机译：双侧乳房重建术和预防性乳房切除术的作用

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Bilateral breast reconstruction may be indicated in women with bilateral cancers, those with unilateral cancer and a high risk of developing a contralateral cancer, or in women who choose bilateral prophylactic mastectomy. Numerous options for reconstruction are available, including TRAM flaps, latissimus dorsi flaps, and saline or silicone gel-filled implants. The discoveries of the BRCA1 and BRCA2 gene mutations and their implications for breast cancer risk have led to renewed interest in prophylactic mastectomy. Recent studies have confirmed that prophylactic mastectomy is effective in reducing breast cancer risk, but the decision to proceed with prophylactic mastectomy must be made on a case-by-case basis.

机译：患有双侧癌症的女性，患有单侧癌症且有发展对侧癌症的高风险的女性或选择双侧预防性乳房切除术的女性可能需要进行双侧乳房再造。重建的方法很多，包括TRAM皮瓣，背阔肌皮瓣以及盐水或硅凝胶填充的植入物。 BRCA1和BRCA2基因突变的发现及其对乳腺癌风险的影响已引起人们对预防性乳房切除术的新兴趣。最近的研究证实，预防性乳房切除术可有效降低乳腺癌风险，但是必须根据具体情况决定是否进行预防性乳房切除术。

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《Breast Disease》 |2002年第1期|23-29|共7页
作者
Susan E. MacLennan;
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作者单位

University of Vermont College of Medicine, Burlington, VT, USA;

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1. Patient Satisfaction and Nipple-Areola Sensitivity After Bilateral Prophylactic Mastectomy and Immediate Implant Breast Reconstruction in a High Breast Cancer Risk Population Nipple-Sparing Mastectomy Versus Skin-Sparing Mastectomy [J] . van Verschuer Victorien M. T., Mureau Marc A. M., Gopie Jessica P., Annals of Plastic Surgery . 2016,第2期

机译：高乳腺癌风险人群中双侧预防性乳房切除术和即刻种植乳房重建术后患者的满意度和乳头-阿罗拉敏感性
2. Impact of Bilateral Prophylactic Mastectomy and Immediate Reconstruction on Health-Related Quality of Life in Women at High Risk for Breast Carcinoma: Results of the Mastectomy Reconstruction Outcomes Consortium Study [J] . Colleen M. McCarthy, Jennifer B. Hamill, Hyungjin Myra Kim, Annals of surgical oncology . 2017,第9期

机译：双侧预防性乳房切除术和立即重建对乳腺癌高风险的妇女健康相关生活质量的影响：乳房切除重建结果的结果
3. One-staged silicone implant breast reconstruction following bilateral nipple-sparing prophylactic mastectomy in patients at high-risk for breast cancer. [J] . Ismail Sahin, Selcuk Isik, Dogan Alhan, Aesthetic plastic surgery . 2013,第2期

机译：高危乳腺癌患者双侧保留乳头的预防性乳房切除术后的一阶段硅胶植入物乳房重建。
4. Using Mastectomy Specimens to Develop Breast Models for Breast Tomosynthesis and CT Breast Imaging [C] . J. Michael OConnor, Mini Das, Clay Didier, Physics of Medical Imaging pt.1 . 2008

机译：使用乳房切除术标本开发乳房断层合成和CT乳腺成像的乳腺模型
5. Comparative study of physical symptoms following bilateral mastectomy with immediate breast reconstruction and delayed breast reconstruction. [D] . Bhat, Ritika. 2015

机译：双侧乳房切除术后立即乳房重建和延迟乳房重建的身体症状的比较研究。
6. Abstract 9. Morbidity and Quality of Life Outcomes of Breast Reconstruction for Unilateral Mastectomy vs. Additional Contralateral Prophylactic Mastectomy: a Cohort Study of 211 Breast Reconstruction Patients Morbidity and Quality of Life Outcomes of Breast Reconstruction for Unilateral Mastectomy vs. Additional Contralateral Prophylactic Mastectomy: a Cohort Study of 211 Breast Reconstruction Patients [O] . Mohamad E. Sebai, Ricardo J. Bello, Eric L. Wan, 2017

机译：摘要9.单侧乳房切除术与其他对侧预防性乳房切除术的乳腺癌重建的发病率和生活质量：一项针对211例乳房重建患者单侧乳房切除术与其他对侧预防性乳房切除术的发病率和生活质量的队列研究211名乳房再造患者的队列研究
7. Bilateral Prophylactic Mastectomy and Immediate Breast Reconstruction in High-Risk Women: The Importance of Health-Related Quality of Life in Decision Making [O] . Valerie Lemaine 2017

机译：高危女性的双侧预防性乳房切除术和立即乳房重建：在决策中存在与健康相关生活质量的重要性
8. Evaluation of a Mouse Model for Prophylactic Mastectomy in Mice Genetically Predisposed to Breast Cancer. [R] . Matory, Y. L. 2001

机译：评估小鼠预防性乳房切除术模型对遗传易患乳腺癌的影响。

Bilateral Breast Reconstruction and the Role of Prophylactic Mastectomy

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