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Investigation of potential aerosol transmission and infectivity of SARS-CoV-2 through central ventilation systems

机译：通过中央通风系统调查SARS-COV-2潜在气溶胶传播和感染性

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The COVID-19 pandemic has raised concern of viral spread within buildings. Although near-field transmission and infectious spread within individual rooms are well studied, the impact of aerosolized spread of SARS-CoV-2 via air handling systems within multiroom buildings remains unexplored. This study evaluates the concentrations and probabilities of infection for both building interior and exterior exposure sources using a well-mixed model in a multiroom building served by a central air handling system (without packaged terminal air conditioning). In particular, we compare the influence of filtration, air change rates, and the fraction of outdoor air. When the air supplied to the rooms comprises both outdoor air and recirculated air, we find filtration lowers the concentration and probability of infection the most in connected rooms. We find that increasing the air change rate removes virus from the source room faster but also increases the rate of exposure in connected rooms. Therefore, slower air change rates reduce infectivity in connected rooms at shorter durations. We further find that increasing the fraction of virus-free outdoor air is helpful, unless outdoor air is infective in which case pathogen exposure inside persists for hours after a short-term release. Increasing the outdoor air to 33% or the filter to MERV-13 decreases the infectivity in the connected rooms by 19% or 93% respectively, relative to a MERV-8 filter with 9% outdoor air based on 100 quanta/h of 5 mu m droplets, a breathing rate of 0.48 m3/h, and the building dimensions and air handling system considered.
机译：Covid-19大流行提出了在建筑物内的病毒蔓延的关注。虽然各个房间内的近场传播和传染性蔓延都很熟练，但是SARS-COV-2的雾化扩散通过多载体建筑物内的空气处理系统的影响仍未开发。本研究评估了在中央空气处理系统（没有封装终端空调）的多载体建筑中使用良好的混合模型来评估感染的浓度和概率。特别是，我们比较过滤，空气变化率和室外空气分数的影响。当供应到房间的空气包括室外空气和再循环空气时，我们发现过滤降低了连通室中最多感染的浓度和概率。我们发现，增加空气变化率从源房中删除病毒，但也增加了连通室内的曝光率。因此，较慢的空气变化率降低了在较短的持续房间的关连室内的感染性。我们进一步发现，除非室外空气是感染的，除非室外空气在这种情况下，否则户外空气在短期释放后几小时，否则增加了无病毒室外空气的一部分是有帮助的。将室外空气增加到33％或过滤器到MERV-13分别在相对于MERV-8过滤器分别降低了19％或93％的连接室内的感染性，其基于100个umsa / h为5亩M液滴，呼吸速率为0.48m3 / h，以及考虑的建筑物尺寸和空气处理系统。

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