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首页> 外文期刊>World Journal of Gastroenterology >Pouchitis and pre-pouch ileitis developed after restorative proctocolectomy for ulcerative colitis: A case report
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Pouchitis and pre-pouch ileitis developed after restorative proctocolectomy for ulcerative colitis: A case report

机译：溃疡性结肠炎的恢复性直肠结肠切除术后发生囊袋炎和囊袋前回肠炎：一例报告

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摘要

We report a case of pouchitis and pre-pouch ileitis, and inflammation in the neo-terminal ileum proximal to the pouch, developed after restorative proctocolectomy for ulcerative colitis. A 35-year old female presented with fever and abdominal pain five weeks after ileostomy closure following proctocolectomy. Computed tomography showed collection of feces in the pouch and proximal ileum. A drainage tube was placed in the pouch perianally, and purulent feces were discharged. With antibiotic treatment, her symptoms disappeared, but two weeks later, she repeatedly developed fever and abdominal pain along with anal bleeding. Pouchscopy showed mucosal inflammation in both the pouch and the pre-pouch ileum. The mucosal cytokine production was elevated in the pouch and pre-pouch ileum. With antibiotic and corticosteroid therapy, her symptoms were improved along with improvement of endoscopic inflammation and decrease of mucosal cytokine production. The fecal stasis with bacterial overgrowth is the major pathogenesis of pouchitis and pre-pouch ileitis in our case.
机译：我们报告了一例眼袋炎和袋前回肠炎，以及在溃疡性结肠炎的恢复性直肠结肠切除术后发展为袋近端的新末端回肠发炎。一名35岁的女性在进行结肠直肠结肠切除术后回肠造口术关闭五周后出现发烧和腹痛。计算机体层摄影术显示小袋和回肠近端有粪便收集。将引流管放置在肛周小袋中，并排出脓性粪便。经过抗生素治疗，她的症状消失了，但是两周后，她反复出现发烧和腹痛以及肛门出血。袋镜检查显示在袋内和袋前回肠均存在粘膜炎症。袋和袋前回肠的粘膜细胞因子产生增加。通过抗生素和皮质类固醇激素治疗，她的症状得到改善，内窥镜炎症改善，粘膜细胞因子产生减少。在我们的病例中，粪便淤积伴细菌过度生长是囊炎和囊前回肠炎的主要发病机理。

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