Changing face of irritable bowel syndrome.

Quigley EM

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Changing face of irritable bowel syndrome.

机译：肠易激综合征的面目改变。

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Recent years have witnessed tremendous progress in our understanding of irritable bowel syndrome (IBS). It is evident that this is a truly global disease associated with significant symptoms and impairments in personal and social functioning for afflicted individuals. Advances in our understanding of gut flora-mucosal interactions, the enteric nervous system and the brain-gut axis have led to substantial progress in the pathogenesis of symptoms in IBS and have provided some hints towards the basic etiology of this disorder, in some subpopulations, at the very least. We look forward to a time when therapy will be addressed to pathophysiology and perhaps, even to primary etiology. In the meantime, a model based on a primary role for intestinal inflammation serves to integrate the various strands, which contribute to the presentation of IBS.

机译：近年来，我们对肠易激综合症（IBS）的了解取得了巨大进展。显然，这是一种真正的全球性疾病，与患病个体的明显症状以及个人和社会功能受损有关。我们对肠道菌群-粘膜相互作用，肠道神经系统和脑肠轴的理解的进步，导致IBS症状的发病机理取得了实质性进展，并在某些亚群中为这种疾病的基本病因学提供了一些提示，至少。我们期待着一种将针对病理生理甚至是主要病因的疗法的时代。同时，基于肠道炎症的主要作用的模型用于整合各种链，这有助于IBS的表现。

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来源
《World Journal of Gastroenterology》 |2006年第1期|P.1-5|共5页
作者
Quigley EM;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类消化系及腹部疾病;
关键词
Irritable Bowel Syndrome; Gut; symptoms 1; Changing; Comprehension;

机译：肠易激综合征;肠;症状1;改变;理解;

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1. The functional-organic dichotomy: postinfectious irritable bowel syndrome and inflammatory bowel disease-irritable bowel syndrome. [J] . Grover M, Herfarth H, Drossman DA Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association . 2009,第1期

机译：功能性有机二分法：感染后肠易激综合症和炎症性肠病易激综合症。
2. Meditation over medication for irritable bowel syndrome? On exercise and alternative treatments for irritable bowel syndrome. [J] . Fredrick Asare, Stine St?rsrud, Magnus Simrén Current gastroenterology reports. . 2012,第4期

机译：对肠易激综合症的药物冥想？在运动和肠易激综合症的替代疗法。
3. Association of the -1438 G/A and 102 T/C Polymorphism of the 5-Ht2A Receptor Gene with Irritable Bowel Syndrome 5-Ht2A Gene Polymorphism in Irritable Bowel Syndrome. [J] . Ulu O Journal of clinical gastroenterology . 2004,第7期

机译：5-Ht2A受体基因的-1438 G / A和102 T / C多态性与肠易激综合症的相关性5-Ht2A基因多态性与肠易激综合症的关联。
4. State-of-the Art Lecture: Irritable bowel syndrome: the new inflammatory bowel disease? [C] . R. C. SPILLE Falk Symposium . 2006

机译：最先进的讲座：肠易激综合征：新的炎症性肠病？
5. Lactobacillus reuteri reduces visceral hypersensitivity and alters gut motility without changing gut serotonin availability in an animal model of the irritable bowel syndrome. [D] . Jakupovic, Jasmina. 2013

机译：在肠易激综合征的动物模型中，路氏乳杆菌可降低内脏超敏反应并改变肠蠕动，而不会改变肠内5-羟色胺的利用率。
6. Vagus nerve assessment via ultrasonography in irritable bowel syndrome. Are there any changes of dimension in the vagus nerve? [O] . Ömer Özçağlayan, Tuğba İlkem Kurtoğlu Özçağlayan, Mücahit Doğru, 2020

机译：通过超声检查在肠易激综合征中的迷走神经评估。迷走神经中有尺寸的变化吗？
7. Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Methods to assess visceral hypersensitivity in irritable bowel syndrome. [O] . Keszthelyi D., Troost F.J., Masclee A.A.M. 2012

机译：肠易激综合征：方法，机制和病理生理学。评估肠易激综合征内脏超敏反应的方法。

Changing face of irritable bowel syndrome.

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